All-In with Chamath, Jason, Sacks & Friedberg - E126: Big Tech blow-out, Powell’s recession warning, lab-grown meat, RFK Jr shakes up race & more

Episode Date: April 28, 2023

(0:00) Bestie intro! (1:10) Google's mixed bag, Big tech leaves the growth phase, macro picture (24:21) AI update: new projects, global enablement, early adoption (37:38) SF CRE continues to collapse,... Gotham City update (47:52) Lab-grown meat: possibilities, potential impact, and major constraints (1:06:47) Quick earnings button and RFK Jr's presidential bid Follow the besties: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg https://twitter.com/GavinSBaker Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast Intro Music Credit: https://rb.gy/tppkzl https://twitter.com/yung_spielburg Intro Video Credit: https://twitter.com/TheZachEffect Referenced in the show: https://www.google.com/finance/quote/GOOG:NASDAQ https://www.cnbc.com/2023/04/25/google-authorizes-70-billion-buyback.html https://www.cnbc.com/2023/04/25/googles-cloud-business-turns-profitable-for-the-first-time-on-record.html https://www.cnbc.com/2023/04/20/alphabet-merges-ai-focused-groups-deepmind-and-google-research.html https://www.theinformation.com/articles/in-google-founders-shadow-ceo-pichai-discovered-the-limits-of-his-power https://abc.xyz/investor/static/pdf/2023Q1_alphabet_earnings_release.pdf?cache=0924cc https://thehill.com/business/3975838-fed-chief-duped-into-fake-interview-with-russians-posing-as-zelensky https://fred.stlouisfed.org/series/JTSJOL https://fred.stlouisfed.org/series/CIVPART https://www.lawnext.com/2023/04/harvey-ai-raises-21m-in-a-series-a-round-led-by-sequoia.html https://www.wsj.com/articles/pricewaterhousecoopers-to-pour-1-billion-into-generative-ai-cac2cedd https://twitter.com/friedberg/status/1651371655774584832 https://twitter.com/mckaywrigley/status/1651291367224807424 https://www.wsj.com/articles/san-francisco-commercial-real-estate-office-buildings-471742ea https://twitter.com/Jason/status/1650974906916671493 https://www.kron4.com/news/bay-area/ex-san-francisco-fire-commissioner-attacked-homeless-people-with-bear-spray-attorneys-say https://www.wsj.com/articles/inside-the-struggle-to-make-lab-grown-meat-12cf46ab https://www.cnbc.com/2023/04/27/amazon-amzn-q1-earnings-report-2023.html https://twitter.com/RobertKennedyJr/status/1649190840198209537  

Transcript
Discussion (0)
Starting point is 00:00:00 I can't wait to talk about Lobgromit. I have been trying to get people to... Oh God! Oh no! Oh please! Don't, let's not get canceled. But the four of us are functional again. We'd like each other.
Starting point is 00:00:16 We enjoy. We look forward to doing this show again. Everything's styled in. Is your lab grown meat that used hormones? My lab grown meat was a little... Let me ask you this about your lab grown meat that use hormones? My lab grown meat was a little... Let me ask you this about your lab grown meat. Do you have to... I just...
Starting point is 00:00:30 I just... I just... I just age. No. No, no. No. You know, I was told that my lab grown meat was a little... I've injected some flavors of tobacco, black cherry, some notes, some notes.
Starting point is 00:00:49 Or Simmons. Oh, not even. No, not. No, not even. No, not even. No, not even. No, not even. No, not even.
Starting point is 00:00:58 No, not even. No, not even. No, not even. No, not even. No, not even. No, not even. No, not even. No, not even. No, not even. No, not even. No, not even. So let's go to big tech earnings. Google stock is up 5%. After beating on the top line and bottom line estimates some high level takeaways, Google announced a $70 billion stock
Starting point is 00:01:20 buy back plan and that their cloud unit was profitable for the first time in its history. As we mentioned last week, Sundar officially announced that deep mind was merging with brain. This is kind of controversial because it's really hard according to some sources where Sundar to get all his lieutenants to work together and row in the right direction. Google's Q1 search revenue up year over year, 2% down 5% quarter of a quarter, just kind of to be expected
Starting point is 00:01:48 because of seasonality and because we're in a down market right now, obviously with the recession. YouTube down 2.5% year over year, down 16% quarter of a quarter, other bets, which is like Nest and some other products down 35% year over year net income 15 billion dollars And he thoughts freeberg on What is a mixed quarter by Google and I guess the
Starting point is 00:02:19 Macro environment what was so striking about the earnings call is not necessarily what was presented, but what was not presented, which was a stronger voice in a strategic plan going forward for dealing with two major issues at the company. One is the operating cost model. And the second is the AI strategy and the response to this evolution in AI. I've heard from a lot of folks that the AI strategy in particular, it's almost like Google already has this in the bag, but they just haven't kind of let it out of the bag. It's like they've got a Tasmanian devil and they're ready to go with it. And there's from my read, an incredible amount of confidence that there's something that's going to happen. And the set of things that are going to happen,
Starting point is 00:02:59 they're going to be very profound and powerful. I even heard some anecdotal stories about, hey, you know, we don't have this feature in this product, but ChatGPT does. And then people basically showed up to this meeting and there was all this debate about, well, we can't let it out because we're not sure, you know, that the classic kind of like we're scared of doing wrong versus leading forward and taking risk. Don't be evil, you're referencing. No, it was just more about regulatory concern and getting things wrong and making a mistake.
Starting point is 00:03:27 And so there's this total fear of like, again, regulatory and fear. So someone kind of slammed the table and said, let's just put it out in the next day they put it out. So there's definitely a cultural change happening internally is what I've heard anecdotally. But what was really missing, which is what Wall Street needed to hear,
Starting point is 00:03:40 what investors and shareholders needed to hear, is what's the strategy there? How are you gonna compete? How are you gonna resolve what's gonna go forward? And secondly, what are the strategy there? How are you going to compete? How are you going to resolve what's going to go forward? And secondly, what are you going to do about the cost structure of the company? Because everyone else, in contrast, a meta being up 11, 12% after hours,
Starting point is 00:03:53 with their cost cutting model and demonstrating that they're going to start pulling cash out of this business. Google's top story was, hey, we're stopping peanut M&Ms in the cafeteria or something ridiculous. And that doesn't really address the real structural question. So I think the stock buyback, the $70 billion stock buyback, is an authorization to repurchase. It's not a plan to repurchase.
Starting point is 00:04:15 So it's unclear if, when or how, that capital does actually get deployed in the market to buy back stock. And so there is also this big kind of shareholder sentiment of being let down that there isn't an improvement in either cash coming out of the business or in cash being used in a smart way with the business. And it was the the silence in the earnings call that I think really stunned a lot of people, which is why you didn't see a lot of stock movement despite the actual
Starting point is 00:04:40 business numbers being better than expected. And so there's a lot that Google I think still has to catch up to with respect to their peers, both on a product and strategy point of view, but also on a cost cutting and a communication of that cost cutting point of view to the market and to the street. Otherwise shareholders are going to start to lose faith if they're not already and are going to start to put their capital with other folks who they feel are better leading and leading into this new evolution of technology like Microsoft and Apple and meta, which is really where those big capital allocators end up picking stuff to go. One final thing I'll say, it's extraordinarily important to note that I think Google has such an incredible AI advantage over Microsoft. And Microsoft is almost solely dependent on OpenAI. This small startup company and all of Bing chats is powered by it.
Starting point is 00:05:35 And Microsoft hasn't built out the infrastructure, the team, the rigor, the depth, the models that Google has. And Google made a few strategic blunders. You know, they shouldn't have been as open with the transformer work that they did and shared that publicly. It certainly enabled OpenAI and others to compete. But Google certainly has an incredible set of tools
Starting point is 00:05:56 and capabilities that is leap years ahead of Microsoft. They're in a position to really compete. They just have to have the will and the leadership to do it. Slam the table, say, here's we're going to stop wasting money and we're going to start leading and driving this industry forward. And this could be a quick turnaround story for this stock and for this company. And I hope it'll happen.
Starting point is 00:06:15 Jamat, what are your thoughts on Google's leadership specifically? Is Sundar the right person to run the company going forward? Does he have the founder authority to get the ship and to get the lieutenants all kind of rolling in the same direction. There's a need to be a leadership change, which is the big discussion of topic in Silicon Valley right now. I think he's very capable. That's in a more of a organization of so many different competing interests.
Starting point is 00:06:42 The thing that doesn't add up about the Google earnings release, but then also what FreeBird just mentioned is there was this article that kind of tried to paint Sundara sort of a caretaker CEO, right, where Larry was the actual shadow CEO. Well, if that's true, you know, Larry has more incentive than anybody else to kind of force change. And there was all these kind of like gripes and complaints that were articulated. And I don't put much stock in all of this stuff. I think that he is the right person for the job. And I think what they have to do is just do the simple basic things.
Starting point is 00:07:21 It doesn't take a CEO change for a board of directors to have the emotional wherewithal to authorize a 15 or 20% reduction in force for a company that is so profitable that clearly is not yet humming on all cylinders. And so you don't need to go through all of this drastic change to do these simple, obvious things. My takeaway across all of these four big companies is we are in a really unique moment to observe something that may sound controversial or hurt people's feelings that like these companies, but I think we're now well-past peak big tech. Their valuations may still go up because they generate such an enormous amount of cash flow.
Starting point is 00:08:09 But these are exactly those kinds of businesses now. They are X growth, large cash flow businesses. Blue chip, you might say? Well, they were always blue chip, but the way that they grow is not through innovation. If you look at Google, Facebook, Microsoft, and Apple, and ask yourself when was the last hugely disruptive thing that they've created? Your heart pressed to find something that was even done in the 2010s. Yeah, actually, that's a good thought. I mean, the iPhone for Apple. iPhone was 2007. Yep. Microsoft was in the 1990s. Google was in 1998 with core search. Maybe there was maps and Gmail and
Starting point is 00:08:47 in the 2000s. Chrome. Android. They bought some of that. Facebook, it was the core service that we built in the 2000s, and then they acquired brilliantly, right? So I'm not saying that they didn't acquire well. Yeah. My point is that core organic innovation hasn't been there for a long time. So this is a moment to just be reflective of the fact that these are some incredible companies with ginormous cash flows. But now you've had this foundational platform shift, which exposes the fact that they really aren't good at innovating. And at times when they've tried to organically innovate, they've massively misallocated capital. Either through a bloated balance sheet,
Starting point is 00:09:30 so someone would claim that Google overspends, or through just pure misallocation by starting projects that just are not large, but consume large amounts of cash that would be the Facebook VR example. But in all of this, I think when you cut staff and expenses as a way to meet and beat, and top-line growth is in the low single digits, it's an important moment to recognize that these companies have now transitioned to being cash cows. And if you look at sort of how financial markets value cash cows, they're very valuable, but it's
Starting point is 00:10:06 not where you look for growth. And so in a world where rates eventually get cut and we start to come out of a recession, it tends to be that other people get rewarded. So that's an idea that's worth. And adding to your point here, they're not allowed to acquire anything. Microsoft's acquisition. The acquisition thing, dead. Dead.
Starting point is 00:10:24 So they're not going to be allowed to buy's acquisition. The acquisition thing dead. Dead. So they're not going to be allowed to buy stuff. So then you're right, what is the growth here? They're not able to innovate. I think these companies are X-growth, which is why they use their cash flows to do what borrow money cheaply to buy back stock to manipulate their equity. You can manipulate and overcome delusion.
Starting point is 00:10:44 You can manipulate earnings per share. you can manipulate earnings per share you can manipulate the number of shares outstanding and so just by the nature of that whole game a bunch of passive investors will end up buying more which helps the active investors who own that stock so it's a game so if we're not in the world financial engineering would be the I mean the most charitable way to say it we're in the financial engineering phase, which is fine. And by the way, you can make a lot of money Facebook's up 90%. So there's a lot of, there's a lot of, meaning just this,
Starting point is 00:11:11 just this here. Oh, yes. So there's a lot of room for financial engineering, but it's not where you need to look to figure out where these big improvements and uses of this next generation platform technology are going to come from most likely. SACs is a fair assessment in your mind looking at the major tech companies, the fangs. Yeah, I mean, their growth is down to single digits.
Starting point is 00:11:33 So I think Microsoft had 7% year-over-year revenue growth. Google was at 3%. I think Facebook was 4% for sales rose 3% 3% from a year earlier, but at least that was an improvement because it's got to be gone down for three straight quarters. So yeah, but you're down to a single digit year over your growth rates. Nevertheless, most of these companies beat expectations. So Microsoft shares rose 9%, Meta jumped 12%, might be up more now and I guess Google got a little bit of a balance and they all gave a pretty upbeat forecast. The only one that wasn't a beat was Google where
Starting point is 00:12:16 the CFO Ruth Porat said that the outlook remains uncertain. But all the other ones seem to indicate that things were going to get better. So I think what's interesting about that is just the mismatch that we have between how well these companies did in this quarter versus how uncertain the rest of the economy is looking right now. And maybe the Fed's behavior? Yeah, so maybe this is the flip side of what you're saying is they're not growing very fast, but they are profitable machines generating a lot of earnings.
Starting point is 00:12:44 And they seem to be pretty immune from what's happening in the economy right now. Or at least that's what they're saying. Now, you're right. In a parallel track, there was an interesting interview that Powell did. So Jerome Powell gave an interview. It was actually kind of like one of these hoax calls where a couple of people were telling to be Solinsky engagement and interview. Oh my god. That was crazy.
Starting point is 00:13:16 What has happened? They've done this a number of times where they've gotten you know major leaders I think they did this to my crone some other people where they pretend to be Solinsky and they do an interview. It's like Olig. Yeah But they played it straight. I don't care that he was fooled into giving the interview. It's like who cares. But some of the things he said were really interesting. I mean, number one, Powell said that the economic outlook for the year was looking pretty uncertain. And he said the most likely scenarios were either sub 1% growth. So staying out of recession, but just barely.
Starting point is 00:13:43 Or he said going into recession. So he thought that was roughly about equally likely. He admitted that we had the worst inflation in 40 years, and that's why interest rates were necessary. And he said that it was necessary to slow the economy in order to combat inflation. And he then even went further and said that it was necessary to cool off the labor market and even to cool off wages specifically because that's how you combat inflation. That's the only thing we know how to do in a situation like this. So I think this is certainly a political mistake for Powell to say that his objective here
Starting point is 00:14:15 is to hurt the wages of the American people and to basically cause a recession, but that is his view apparently. And I think that we are headed for, it seems like a recession. I'm a little surprised that the earnings reports for these tech companies are so good because, or at least their forecasters are so good. Well, they can cut spending. And we talked about this last year when we were trying to predict what would happen. I remember saying, well, I think, at Jamathan, I were talking about this and I was like, well, at Jamathan was saying, hey, earnings are going to go down
Starting point is 00:14:41 and there's a PE and I said, well, what if they just stop spending or they make a lot of cuts? Well, here we are. People are just saying, you know what hey earnings are going to go down and there's a PE and I said, well, what if they just stop spending or they make a lot of cuts? Well, here we are. People are just saying, you know what? We're going to cut our way to and do stock buybacks. That's another way of financial engineering to route around the Fed, right? And to make the stock go up. Worked incredible for Facebook.
Starting point is 00:15:03 I mean, my lord, they were at $91 a share and they're over 200. Right, but just to bring it back to the economy. So look, I think we agreed that these tech companies seem to be pretty immune. They've got a large cushion in terms of their ability to continue generating earnings because of all the bloat that actually gives them like a margin of error where they can just keep cutting to prop up earnings. I'm a little surprised that they think their revenue forecasts are gonna be so positive
Starting point is 00:15:27 because again, they were guiding upwards generally. So they seem to think they're not gonna be impacted by the recession and maybe they won't be. Again, I think what was interesting from Powell is the way that he seemed to think that the only thing we know how to do, this is basically what he said, the only thing we know how to do
Starting point is 00:15:43 in the situation with inflation, is to kill the economy, it's to slow the economy, and specifically to kill jobs and wages. And that was pretty remarkable to me, because there are other things we could do. Such as. Okay, well,
Starting point is 00:15:57 one thing is that you don't have to print so much money. Cut spending austerity. So yes, our fiscal policy remains completely out of whack. We're running $2 trillion annual deficits right now, past COVID. So he could have said, listen, we could get off this reckless fiscal policy and be more restrained, but he didn't want to go there.
Starting point is 00:16:15 The other thing he could have done was address the supply side. One of the ways that you can reduce inflation, it's not just to kill demand, you could actually affect supply chain. So like cost of energy, for example, Energy is a huge input into the economy. And one of the things that happened at the beginning of this administration is they made it much harder to drill for oil and gas. And I think Biden sort of reversed course on that. At the state of the union, remember, he had that line where he said, we can't get off oil and gas for 10 years
Starting point is 00:16:42 and the audience started laughing. But in any event, the point is just that it's too little too late. They could have done more on energy to keep cost low. And then there's a whole bunch of other critical inputs in the economy besides labor. And what you could do is I think you could go category by category and say, how do we get the price of these key and puts into our economy down? How do we resolve supply chain bottlenecks?
Starting point is 00:17:04 How do we make it easier to get access to whatever the key commodity is? I think there's things they could do if they're just willing to work at it. Maybe this isn't the Fed's job. This is more the administration. You could do it, say, listen, we're going to make it easier for people to produce and create supply. If you have a higher supply of goods and services, then you will start to bring inflation down. Because inflation is just the amount of money in the system divided by the
Starting point is 00:17:32 amount of goods and services. And when the amount of goods and services hasn't gone up, but the money supply has gone up tremendously, you're going to have inflation. And that's why I think it's a little bit misplaced to be killing demand the way they're killing it is, because fundamentally, the problem here is they flooded the economy with money, both through government stimulus and through quantitative easing, and then also they made it harder on the supply side to produce, certainly with energy. So it seems to me that the approach
Starting point is 00:17:59 they're taking for us to get out of this, it's like taking a meat cleaver to the economy, or a sledgehammer, really. And it's the most violent possible way that they could solve the problem they previously created of too much inflation. Any other thing, obviously, is jobs. We're still sitting here with close to 10 million job openings. And the thing I'm hearing from the streets is that unemployment hacking is become a high art. And so labor force participation remains low. It's nowhere near the historic highs. We have been very permissive during
Starting point is 00:18:34 COVID for good reasons to give people very extended benefits. People have now learned is my understanding. And this is something that's happening on a regional level and state by state level. People are learning how to hack unemployment and not going to work and people are just not taking the jobs that are open, which are service industry jobs. Americans don't want to work them. We don't want to let people into the country. We got to record low people coming into the country. It seems to be a much more productive way to do this, right? So I think it's an excellent point because exactly what you're doing there is addressing the supply side, which is you're unlocking the supply of a key input into the economy, which is all this unused labor.
Starting point is 00:19:11 It's all these people aren't working. You're right, the labor force participation rate is still much lower than it could be. So if you get more people into the economy, then that helps alleviate the cost of labor, it helps fill these jobs, but it doesn't kill the economy. So it would be a much more positive way to address this. So I just think it should allow a creativity for him to say that the only thing we can do in this situation is not just to raise rates.
Starting point is 00:19:36 He did say that, but to go further and cool off the job market, increase unemployment, and cool off wages. I mean, that's going to be a very unpopular thing to say, I think, because what you're basically saying is you're going to hurt the wages of the American people. Who wants that? Here's the chart for job openings. We thought this would collapse.
Starting point is 00:19:57 It went down, certainly, as we, you know, I don't want to obsess over macro stuff, but it's still way up there. And so the fact that we can't get people to take these jobs, I don't know, Chimoff, what do you think about the employment and participation situation and how that might unlock things? I also wanted to know from you, Chimoff, this concept of the Fed is reacting to data just so slowly
Starting point is 00:20:21 and then you have these companies that maybe are more nimble and they have better data than the Fed. I think that that's the truism and I don't think anything about that is going to change. I mean, I think we talked about how these folks calculate non-farm payrolls or how they calculate CPI. It's incredibly outdated, right? It's people with clipboards walking around, talking to people and checking boxes and filling out forms. Can that change? Probably it could.
Starting point is 00:20:48 Will it change? It probably won't. And so they're going to focus on the most simple but most powerful measure that they have, which is controlling the money supply. And of what SACS talked about. So they're going to manipulate the money supply to either put more liquidity in the system, in which case markets go up and asset prices go up. But then inflation goes up, or constraint liquidity, which then causes markets to go down, asset prices to go down, and inflation eventually
Starting point is 00:21:15 to go down. The thing that we're facing today when you look at this labor market chart is a couple of things that I think we've talked about before, and I just want to reiterate them, which is chart is a couple of things that I think we've talked about before and I just want to reiterate them, which is you have to remember that we're in this new world order, which is the X China world order. And in that, there is no more unitary economy that can do things cheaper, faster and better globally around the world. So we're going to near shore or or on shore all kinds of things that used to be done by the Chinese They'll sit in Mexico or they'll sit in Central America Maybe in some cases they'll sit in Canada and all of that will feed into the United States The problem with all of that is that that will keep costs higher because it'll be naturally more inefficient
Starting point is 00:22:01 it will naturally take more money and that will naturally cause the prices of those things to be higher, which means that terminal inflation, I think, is just roughly higher. As a result, I think that more power, if you will, goes to labor. So in this constant tension that we have in an economy between labor and capital, the people that own the factories or the businesses and the people that run them and work inside of them, we've been in this position where the pendulum has swung so far towards capital,
Starting point is 00:22:34 the owners, the shareholders that all this financial engineering has tremendous upside, right? That's why companies engage in it. But when you show that chart, Jason, what it means is, it's just really hard to find people. And so the only way you're going to get people off their butt to go into work, to sit in a chair, to do a job that you need them to do is to pay them more. And in finding that, wages will have to go up. The counterbalance of that is what AI will do, which I think I was about to say, that is the key, which is massively
Starting point is 00:23:05 deflationary. So that is going to be the tension that we're in now for a really long time as we explore this. I don't know if you guys saw today, but Sequoia let a $20 million around in this thing called Harvey.ai. The legal, which is like a legal super wizard for law firms. Yeah, we knew that was coming. And my partners and I were debating it. And what
Starting point is 00:23:25 we thought of was, well, how much do you pay out of the $800 or $1000 an hour that you charge to Harvey dot AI? Maybe you're willing to pay 5% or 10%. But then the reality is that one of the most powerful things it does is is able to go into West law, find all these cases and say, yeah, this is germane to the thing that you're working on right now. That's a very useful thing. But the N plus first law firm will also use that tool and instead of charging $800 an hour, they'll say, well, we'll charge $600 an hour and we're still willing to give you
Starting point is 00:23:56 5 or 10%. So I just don't see a world where on the one hand, physical labor will continue to be more expensive. where on the one hand, physical labor will continue to be more expensive, they'll demand more and more money to do the job that they're asked to do. And the knowledge work will become increasingly more deflationary because so much of it will be automated by AI that those folks will charge less and less. And there's going to be attention there, and I don't exactly know what's going to happen. I did a couple of experiments this week.
Starting point is 00:24:23 I've been rolling up my sleeves and playing with these tools. It's pretty amazing. And I would try and to use them for actual tasks in our companies. What have you learned? What did you do and what have you learned? So I got on the OpenAI plugins, Greg. Thank you.
Starting point is 00:24:40 I sent him my email and he got me onto that. And you can connect it to Zapier. So I have two projects I'm working on currently. One of them, I was, since I'm raised in Washington for it, I'm actually going out to people not just taking inbound. I was like, hey, can I get the names of all the major LPs and start doing some research there, putting a table, stuff that's actually what he does blog post. But then I started connecting it with finding people's Twitter handles, finding
Starting point is 00:25:06 their LinkedIn profiles. And then the next piece I'm working on is automatically following them, DMing them on Twitter, let's say, or following them and doing an in-message saying, hey, we haven't met. Here's the deal memo for my next fund. We'd love to get together. This is sent from Jason's AI script. I was going to actually tell them, but here's my real email. If after you read the summary of the next fund, you want to meet. And then I was, I'm going to pair that. And this is a piece I'm going to probably need a developer to do with our internal LP database to not email people who are already duplicates. And then inside with newsletters, I have it building a database of every newsletter
Starting point is 00:25:45 we've ever sent, the writing style, and then I'm having it go find in real time news stories that we should be including in the newsletters, which I think will make the writers right now a third, more productive. But these are things that would cost 40, 50 bucks an hour, 30 bucks an hour for college educated Americans and Canadians. And I have already figured out, and I'm not a developer anymore, I had to script them and I'm actually thinking about learning to code again, just so I can do this myself. And so on Saturday, I'm going to do a little coding with a friend of mine and get back up to speed
Starting point is 00:26:20 on that. I think about 30% of what knowledge workers do right now is possible. So I put every single person at both companies on Chatchy PT4 and the playground. About 30% of what knowledge workers at both firms can do currently is doable if you can figure out. And this stuff is not perfectly scripted yet. So I've been doing some stuff in travel as well, playing with the kayak, interface, Expedia interface, etc. To look at travel planning and it's pretty good as well. So it's,
Starting point is 00:26:57 it's, this is the real deal folks. I think by the end of this year, 30% of knowledge work could be done by this. And then additionally, on Monday, I went back to work in person and I went to, I hosted our accelerator in person and then I hosted Founder University in person in the city. The city was absolutely dead. But we had a hundred people fly in from around the world for our Founder University and a lot of them were working on AI projects. And what's very interesting is like there's this big debate going on freeberg between is this going to be built into chat GPT-4 or Bard or, you know, Poe or whatever
Starting point is 00:27:35 it is or should I even bother so should I bother building, you know, a verticalized app? And it turns out like I think you should do the verticalized app. And you're going to be able to put together multiple of these a eyes that have different specialities. So I'm super stoked about it, but I do think if you're not using this, if you hear my voice right now and you're a white collar worker and knowledge worker and you're not using this. This year and getting up to speed on it, I think you'll be out of a job within the next two. She's well. I just don't think you'll compete. It would be like trying to compete without knowing how to use Microsoft Office 20 years ago, right? Like could you work and not know email? Remember when we came into the workforce 30 years ago and some people knew office and email and web research and then other people
Starting point is 00:28:25 didn't. Those other people retired. They were phased out. If you didn't know how to use a computer and type and use an Excel spreadsheet or do a PowerPoint, you were done. I think there's two possible ways you can interpret what you're saying. So in terms of the economic impact, so one is that you could say, well, AI is going to do 30% of the knowledge work. Therefore, 30% of the knowledge workers are going to be put out of work. I think a different way to put it would be every knowledge worker can get 30% more work done. So if that's the case, then they're more productive. And we're just talking about the problem of how do you increase real wages in the economy without having inflation?
Starting point is 00:29:01 Well, the way to do that is for every worker to be more productive. So if every worker is 30% more productive, in theory, their wages should be able to go up by up to 30%. That's how you get wage growth. Now, maybe there will be some companies that don't need all those employees because now they're able to get whatever or third more done, but there will be other companies who can hire them. They can go off and do other jobs for other companies, especially when you've got this backlog of, like you said, eight
Starting point is 00:29:27 or 10 million new jobs that are on. Those jobs are all service, though. You know, they're not. You're actually going to have this big group of knowledge workers, but there's just nothing for them to do. I just don't. I agree with you, but I think there's going to be a group of knowledge workers who do not embrace this and do not make the transition because it is, it's going to require an upskilling. I think you're actually going to need to know how to do some basic programming and coding to really take advantage of these, at least like scripting level stuff. I don't know, it's pretty easy to use. I agree with you there, but you go.
Starting point is 00:29:57 Writing blog posts, but the example I gave of like taking the LP database, sorting it, you know, it's not quite very hard. This is like a chatbot. It is. Like, I think it takes like level two programming skills. No, it doesn't. No, you don't have to know the program. You just have to know how to prompt it in natural language.
Starting point is 00:30:16 It's the option of need to learn how to code. The thing that makes coding hard is that you have to learn the specific commands. It's like it's own language. You have to learn a new language. With this you don't. In fact, one of the cool things about some of these OpenAI APIs is that you just tell it what you want it to do. There's not even like a scripting language.
Starting point is 00:30:35 Love it's in natural language. And that makes it incredibly easy to use, even for developers. So I don't think this is a hard technology to use. I agree with you, there may be people who are resistant to it because there's always people who are resistant to change in new technology and you're right. If they don't adapt, they're gonna be dinosaurs.
Starting point is 00:30:52 But I don't think this is a hard technology to grow out how to use and get benefit from. You might be right. I mean, right now it's so new that the glue between systems is just not there yet. And maybe you'll be able to talk to chat GPT-4, and it'll connect your database on Notion. It will take a type form and a survey monkey
Starting point is 00:31:12 and put it all together and figure that all out for you. That's a whole game right now. It's still connecting all these things. And that's what I'm talking about. And that's kind of not there yet, but in the auto GPT stuff, you need a developer right now. But anyway, I'm deep in it. And I am more excited right now.
Starting point is 00:31:29 This feels to me like 2005 to 2012 period when you just saw Ajax and the web and speed just all coming together so quickly. And the rapid iteration is just unbelievable. Every day I find a new use for it, I have made my default webpage opening. Like when I open a new page on my PC, it just opens chat to PT4 now. Just so I'm forcing myself to use it for every possible task. And the people who work for me, some of them are doing it, most of them are not. And I'm just trying to drag everybody along.
Starting point is 00:32:05 And then you have at the same time this remote work thing happening where salaries I'm finding are starting to normalize not across cities but across countries. So you know hiring somebody in Canada, Estonia, Sa San Paulo, and then you add this AI to it, the cost to do things is, this is like, I don't know, I think everything's gonna cost about 10, all this knowledge work is gonna be 10% is expensive to do. I don't think it's 10% less, Jamath, or I think it's like 90%, 10 cents on the dollar.
Starting point is 00:32:42 10 cents on the dream. I agree. I agree. I agree. And it's not, this is not a five year 10 year prediction. This is like five quarter 10. By the way, we said that the first organizations to use this, like the Canary and the Coal Mine would be the consulting organizations. And today when Harvey got announced, one of the things that that right on the heels of that price water, as Cooper's announced, like a billion dollar investment into the, which makes sense because as a consulting organization full of lawyers and accountants
Starting point is 00:33:09 and IT folks those are the services jobs that you get tremendous leverage if you were to use these tools. Freeberg any thoughts? I don't know I mean I think we kind of beat this horse to death. Right. We've talked about it for a couple months and I think we just keep repeating ourselves. Are you doing anything when you're first hand? Are you playing with it yourself? Yeah. Look, I talked about that. By the way, one thing I will say, we all talk about cost reduction and then, oh, knowledge work is dead and we're going to save money and all this stuff. That is always the first reaction to any new point of leverage realized from some novel technology. The second is suddenly people start doing things that use that leverage to do things that they couldn't have done
Starting point is 00:33:53 before. So it's not just about dropping costs, it's about enabling new things that does 100 times more unimaginable things prior. And I think the next phase of this AI shockwave that kind of hit us and hit the world and kind of hit enterprises is going to be the evolution of integrating those tools in a very unique way with other tools to drive very novel things forward to create new things, new projects, new progress that was unfathomable before.
Starting point is 00:34:24 So it's not just about cost savings, it's gonna be about new stuff. I shared a link on Twitter yesterday. There was some guy, I wanna quote him correctly. His name is McKay Riggley. So it shut out to McKay. On his Twitter page, it says that he didn't know how to code in 2019.
Starting point is 00:34:45 He learned how to code for the first time. He taught himself. And he put together an object recognition tool with chat GPT. I saw this video with his webcam. And basically, he holds up like a Diet Coke and he's like, you know, tell me how many calories, what is this and how many calories are in it. And it's like, oh, there's no calories in it. It's a diet coke. And he does this three different times with three different objects. And he hacked this thing
Starting point is 00:35:12 together in a couple of hours. That is a product that was like theoretically unfeasible or, you know, kind of very, very difficult to kind of see how you would put that piece together quickly and easily with one person in a room in a few hours a year ago. And here you see a demo of this person who didn't know how to code not too long ago putting it together and creating this product that would have been such a profound startup. Imagine if you went to VCs 18 months ago and were like, look, I've got this thing and I hold stuff up in front of it and it tells me all about it and it talks to me and I literally use my voice to talk to it. And he basically strung together a text-to-speech, chat GPT, an object recognition tool, all of this stuff completely open source and a plugin that does web browsing.
Starting point is 00:35:57 And the whole thing is basically like your own interactive visual robot. It's an incredible product demo and I thought it was so amazing and profound. I sure it's a prototype, and it's kind of janky, but it was done in a few hours on almost a no-code basis. It's incredible. So what's gonna come from that is a whole set of new products and ideas and things that we are certainly not thinking about today,
Starting point is 00:36:20 but in six months is gonna become almost Mainstay and many new categories of products, many new industries, many new businesses are going to emerge that we're not even thinking about. So the lead-eyed argument of, oh, this is going to destroy jobs and destroy the economy and drop costs by 90 percent, lawyers are going to get cheaper, et cetera, et cetera. I think that doesn't even matter. It's the tip of the iceberg. What's more exciting is all the new evolutionary stuff that's going to hit the market, that's
Starting point is 00:36:43 really going to transform the things that we can do and that we didn't realize we could do. There's going to be incredible analogy for this because what you're really talking about is more people being able to use tools and be creators. What happened in the 80s and 90s when the NBA started playing exhibition games around the world was more people around the world started playing exhibition games around the world, was more people around the world started playing basketball and then you started seeing people like Luca or before him y'all may
Starting point is 00:37:11 Matambo, you started to have people from around the world who had never been exposed to basketball, just incredible, porzinga, incredible talents emerged because you just had more people playing with the basketball. I think you're gonna have more people playing with code and building products, so you're going to have more people playing with code and building products. So you're going to have incredible amounts of creativity from people who maybe you didn't expect
Starting point is 00:37:32 because they didn't go to school for coding or have that opportunity. Hey, I mentioned I was in Phi Die and I was at a family office in the Wilson, since the end of the year. thigh diet. And I was at a family's office in the Wilsonson Cinees offices to law firms, being the law firms in the financial district in the market. It was an absolute ghost town. And when I say ghost down, I mean, like serious ghost town, like weird, like this is still like being in some dystopian science fiction, then we're the last man on earth. And then we saw in
Starting point is 00:38:03 the group chat today, 350 California Street was worth 300 million dollars four years old. It's a 22 story glass and stone tower, some picture of it. It's going up for sale. And they believe, according to the Wall Street Journal, that bids will come in at 60 million dollars, and 80 percent decline. And we talked about this commercial real estate would have this moment, a lot of the banks, the small original banks own this debt, SACS, what do you think is gonna happen here?
Starting point is 00:38:34 Who is the person who would buy an office tower in downtown, even at an 80% discount, knowing that you have to pay all those carrying costs. And there's so much vacant office space and it's only increasing. Right. What's your who buys this? It's called land banking. Okay.
Starting point is 00:38:56 Explain. So in other words, okay, what I mean is you're right, there's 30% vacancy and San Francisco right now, maybe going up even more in the next few years as Lisa's role and people take less space. You may have a countervailing effect in terms of new companies moving back because of AI or expanding. So it's possible you start to see some growth in the office market in San Francisco. But the bottom line is 30% plus vacancy is going to take years and years of growth in order to absorb. So, you're right, this building, they can slash its rent, but they still probably can't fill it.
Starting point is 00:39:31 I mean, there's just no demand. So, you're going to be sitting on that property for five years, ten years before the market comes back, the way that you needed to. But there's some value. Right. It's going to trade way below its replacement cost. Right. If you were to build to trade way below its replacement cost. Right.
Starting point is 00:39:46 If you were to build that building today, it would cost you many times what they're going to pay for it. The problem is, you can't finance that purchase with debt because the building is not going to generate enough revenue. So that's why I mean by land banking. It's going to have to be an equity investor who is willing to think long term and say, I'm going to buy this at a super distressed price and I'm just going to sit there and hold it and wait. Carry it, like you said, bear the carrying costs until the market comes back. But, Jake, I want to say something. I think it's a great analogy because public growth
Starting point is 00:40:15 stocks have declined 70 plus percent since the market started to decline. We've talked a lot about the statistic that I've shared a bunch publicly on how 70% of publicly traded companies that have gone public since 2020 are trading below their total cash invested since founding, which should translate to an estimate that call it somewhere in the order of 70% of private companies are probably worth less than their preference stack. And so they're not worthless companies. They just have a capital structure that is upside down. Those companies are probably worth less than their preference stack. And so they're not worthless companies. They just have a capital structure that is upside down. Those companies are making products for customers.
Starting point is 00:40:50 Those customers are paying money for those products. There's value there. There's real value there. The value has just been reset. And so it's interesting. It's not just the asset class of growth stocks and the asset class of private companies or private tech. It's also in commercial real estate. We try and treat each of these as if they were in isolation,
Starting point is 00:41:09 but the problem is many of these assets were funded with some degree of leverage. Preferred stock is leverage, and it is a form of debt because it has a preference over the shareholders, they're the common shareholders, the equity holders. The same is true with this commercial real estate market that there was a certain amount of debt because it has a preference over the shareholders, they are the common shareholders, the equity holders. And the same is true with this commercial real estate market that there was a certain amount of debt. So the availability of low-cost capital, I'm securedized against the asset in the form of debt or in the form of preferred stock in a private company, has the same effect, which it allowed the valuations to balloon on the equity. And now that the market has re-rationalized the the price is down 70 plus percent across all three of these connected, but somewhat disparate asset classes, you're kind of having this
Starting point is 00:41:50 big reset moment. And funny enough, the other statistic is the cell phone traffic down 70 percent in downtown SF, right? So it's funny all four of these numbers are pretty much on track. There it is. This chart is crazy. It's literally like you have some cities that have more cell phone traffic Then they did last year or a couple years ago and this is downtown by the way Yeah, I'll tell you that yeah, and Sam I mean the wider Bay area is I don't say booming, but it's vibrant Yeah, I said on last week's show I was looking for a place to host the accelerator in Sam Mateo area I got dozens of people contacting me, hundreds of locations, and offers at 25% of what their carrying cost is, or like, and not the carrying
Starting point is 00:42:34 cost, the rent was, and people offering the major companies, offering me free space, just because they would like to have founders hanging around. And there was one project that I really liked, the person was like, I'll give it to you for whatever, just because they would like to have founders hanging around. There was one project that I really liked, the person was like, I'll give it to you for whatever, just because I want to get more people to downtown San Mateo. So that does sort of prove to the point that there is a... I saw this in New York City during the 90s. When things were so cheap, people just got creative with space. It inspired people to say, I'm going to create an art gallery,
Starting point is 00:43:03 I'm going to create a performance space. I don't know when that happens in San Francisco with these spaces, but feels like it's going to be a while. I don't know what you, when do you think there would be demand for this space, sex? If you had to pick a year and give us an over under, I mean, five years plus, I mean, just to give you some numbers, I think a healthy vacancy rate in the office market is 5 to 10 percent. A high vacancy rate in a city was considered like 15 percent. Like you wouldn't want to be an office investor in a market that had 15 percent vacancy. 5 to 10 percent was sort of the normal range.
Starting point is 00:43:42 If you were under 5 percent, it was a super hot market, and then 10 to 15 was sort of a not great market from an investor standpoint. So there are 30% plus. And like I said, it could get worse before it gets better because as Lisa's role, people are gonna shed more space that they might not already be sub-leasing. So the real number might be like 40%. Psh.
Starting point is 00:44:04 So I think it's like, yeah, it doesn't seem like a decade. So it's a decade assuming that San Francisco gets its house in order and companies come back. Speaking of that, new companies are created and they don't completely wreck it. It's not clear to me that things will go in the right direction. I mean, speaking of that, do we want to bring up this horrific bear spray attack now? You want to cue that up, Sox? I mean, we're like in full-on Gotham City now.
Starting point is 00:44:31 Now we have vigilantes. There was a story of a fire commissioner named Don Carmoniani who was beaten with a metal pipe by a gang of homeless addicts who were encamped in front of his mother's house. And apparently they were harassing her and they were doing drugs, smoking drugs or whatever, right in front of not pod. It was like, federal, whatever. Fend all or math or crack, something like a hard drug. And so what we know is you went down their head words with them, about a beep, about
Starting point is 00:45:04 a boop, you know, and they bashed him upside the head with a pipe. And now it turns out that he was accused by the defendant's lawyer, the one who assaulted him, so we don't really know what's true here, of using bear spray on them first, so the DA dropped charges. The lawyer for the defendant in that case is saying that he apparently was the perpetrator of these bear spray attacks on homeless people going back a number of years. I guess there's a, like you said, pretty gnarly video of that. We don't know that.
Starting point is 00:45:38 We don't know that. But obviously, the DA thought something was kind of hinky because they dropped charges against the guy who assaulted him We shouldn't The person who sprays the bear spray and the person who beats somebody with a pipe shouldn't both people Yeah, yeah, of course listen There's video of somebody bear spray homeless people and that's clearly wrong However, that was from a couple of years ago the one that was released is from 2021
Starting point is 00:46:03 we have video from the night that Carboniani was assaulted that they were chasing him down the street. They're chasing him down, yes. With the metal pipe. Even if they're acting in self-defense, you can't go chasing the guy to the self-defense. That's self-defense. More damage on him. Exactly.
Starting point is 00:46:22 That's vengeance. That's not self-defense. Yes. So they took it out of that zone of self-defense and they were chasing after him. And if you saw what he looked like after the attack, they were using deadly force, he could have been killed. And you know, if Donna got killed by the metal pipe, I don't think it'd be a defense that he bear sprayed them first. No, he just did that.
Starting point is 00:46:42 It would have been an excessive use of force. So, but in any event, I mean, where the DA ended up on this, it was just a drop charges from that night. But you know, that they're going to drop those charges. I think that that's going to be untenable. No, they're ready. They already dropped the charges. They have to, I mean, justice has to be blind, correct? I mean, you're a trained lawyer here. We have to apply the law equally to the sadistic insane person who, wait a second, they arrested the guy who hoes the person down. Didn't they arrest them as well?
Starting point is 00:47:12 I remember seeing a perp walk, talking about that on the previous show. Anyway, it's Gotham City folks. This is gone to pure insane level. Yeah, I don't think this just proves anything. I mean, again, what they're trying to say now is that because of the actions that Don took, that San Francisco is safe, and there's only a worry about. Again, what they're trying to say now is that because of the actions that Don took that San Francisco is safe and there's nothing to worry about. These paddocks, people who are encamped on the sidewalks doing drugs, doing hard drugs,
Starting point is 00:47:32 there's nothing to worry about because somehow they were provoked by Carmen Yonni. I just think I agree with you that this is part of an overall pattern of chaos and law assistance in the city. It is like athem city. It doesn't know, it doesn't make me feel a lot better about what's happening on the streets. It's nuts. Chimathi wanted to add something. A lot of freeberg to...
Starting point is 00:47:53 Oh, Riffon, glad me. Oh, yes. Well, there was actually a story about this. I guess there's two types of lab... There's two types of mock meets. I've had the impossible burger. I've never craved an impossible burger There's so many great burgers you can get out there shake check five guys in and out Why would I go to get this impossible burger unless I was doing it like vegan stuff?
Starting point is 00:48:13 But then there was also supposed to be 3D printed meats and this stuff seems to be taking forever Where is this at because there was a story in the Wall Street Journal about how poorly this is apparently going so there's three categories of these alternative proteins, the traditional animal protein. The first is these, call it alternative proteins, where you use things like soy protein or pea protein. Beyond burger is a good example. They have a pea protein based burger. And so that category was kind of hot for a minute where everyone is like, oh, it's an eco-conscious decision. People will make the shift. And beyond meat had this massive IPO and the stock went crazy.
Starting point is 00:48:59 And I, someone said it was the biggest return ever for Kleiner Perkins, but it really was just taking plant protein, processing it, and trying to make it sort of mimic the texture and flavor and taste of animal protein. And it's more expensive. So I've generally been fairly negative on whether that really moves the needle, right?
Starting point is 00:49:16 The needle for me is can you replace animal proteins traditionally, and stop using all this land, and putting all this carbon into the atmosphere, and all this water, and all these resources that we use to make all these animal proteins, which I think is both kind of ethically incorrect but also extraordinarily environmentally costly. Sorry, can I ask a question? Qualifying question. Do you think it's also important for it to not just replace natural products, despite
Starting point is 00:49:39 all of those externalities you talked about with artificial products, with chemicals and sugar? So, first of all, everything is a chemical. So, I think the the categorization of all chemicals are bad is silly because everything is made of chemicals. I think it's a question of are there bad things that are being put in there that's not good for your health to make it flavorful or whatever, and that may or may not be the case. It's really product dependent. I don't think it's a good generalization. But do you, so you think when I eat a salad, I'm just eating chemicals?
Starting point is 00:50:09 It is chemicals, yeah. Got it. But what if he was? Healthy chemicals are in the salad. There's good in there or bad, yeah, for sure. And then bad chemicals are in like sugary cereal. Yeah, like refined sugar is bad for sure, right? That's a bad chemical.
Starting point is 00:50:22 And I, no, I'm just, I just want to understand how you just viewed as a spectrum of chemicals, some good good some bad. Yeah, there's things that are good for you. There's good fats, there's bad fats, there's, you know, and even in the category of sugar, some people say all sugars are bad, some people say some sugars are better than others as measured by the glycemic index. You know, there's a lot of ways to kind of look at this stuff. It's beyond meat and these P1s, they're all processed, highly processed. They got a lot of salt, they got a lot of fat, right? They're not good for you.
Starting point is 00:50:49 So the way that beyond and impossible and others have tried to make it taste good for people is they've added a lot of saturated fats, which is a way to drive the mouth feel and make it taste good. But then a lot of doctors, the American Heart Association came out and said that those fats are really bad for your heart and you shouldn't eat them. And also, there's been a general kind of consumer sentiment shift.
Starting point is 00:51:12 So a couple of years ago, these were the hottest products. It was like all the food ingredient companies were shifting to plant-based proteins and they were building plant-based protein business categories. And it was this big hot thing. And then they came out and they're like, wait a second, this isn't going as we thought. What happens is people try them out and they're like, yeah, that's a cool thing. I wanna do good for the planet.
Starting point is 00:51:30 But would I rather pay five bucks for a do good for the planet burger that kinda doesn't taste that good? Or would I rather pay three bucks for a burger that tastes really good? And what happens is, B, I choose option B. Yeah, and so to most people, right? And so almost all people, and that's the point I view.
Starting point is 00:51:46 I've always shared. I said, it's just, it's not going to win the hearts and minds of the world unless it's cheaper and it's tastes better. And healthier, and healthier. Yeah, and doesn't damage your health, doesn't make you worse. Exactly. So the more challenging technical solution is the other two categories.
Starting point is 00:52:00 The second category is, can you synthesize animal proteins using recombinant DNA? So this is where you take the DNA that codes for the protein, whether it's the milk protein or the egg protein or the cheese protein, and you put it in a bacterial cell or yeast cell that are used to ferment, that we used to make wine, that we used to make beer, and they each sugar, and then they spit out a product. And in the case of wine and beer, they eat sugar from grapes or from malt or whatever and they spit out alcohol, ethanol. And Genentech was the first company
Starting point is 00:52:31 to really pioneer recombinant DNA at a mass scale. They basically used recombinant DNA to make insulin. So they took the DNA from humans that codes for insulin, the gene for insulin, they put it in E. coli bacteria, and then they put the E. coli bacteria in a big tank, and the E. coli start to duplicate and they make all this insulin. And that's how we make all the world's insulin today. It's using that bio-manufacturing process.
Starting point is 00:52:53 And it's how we make all of biologic drugs. All anybody drugs are made this way. It's a $300 billion dollar your market just in biologic drugs. So when CRISPR kind of came about in 2012, suddenly the toolkit to go in and do a much better job and a much cheaper job of editing the genomes of the little microbes to make a more efficient at making these proteins became standard. And everyone said, let's go use this new category of what's being called synthetic biology or symbio to make all these animal proteins that we use animals to get today. So, can I just ask a question? Is the idea that if you use recombinant DNA in this process,
Starting point is 00:53:27 it would taste better and be healthier and all this? Chemically identical. So, it's the exact same protein as you would get... Panders, I understand it would be the exact same under a microscope or whatever, but would it taste the same? Taste exact same, totally. Exact same. So, that's the whole thing.
Starting point is 00:53:42 But, doing, do we know that or was that that was the guess? No, we know that. It's the same protein, Shema. So, whether you get the whole thing. But doing, do we know that or was that that was the guess? Now we know that it's the same protein schema. So whether you get the protein from the cow or you get the protein from the yeast cell, what's the issue with the same protein? It's too expensive to do this process. It's expensive. So the key metric in that second category is productivity, grams per liter per day. How well can you get that little micro organism to make that protein?
Starting point is 00:54:04 The more protein it makes per day, the cheaper the price per protein, and we're still a far ways off from getting this to be price competitive. So that's a challenged category right now. There's a lot of, I'm invested in a couple of companies in this space where we're trying to make it faster and cheaper to do that strain engineering to edit the genome up front and make those little cells more productive to bring the price program down and hopefully make it compete ultimately with the traditional market for eggs, cheese, milk, etc. But what is the constraint? Is it an energy constraint or is it natural biological in capability? No, so the great thing is our first principle's basis, the biophysics indicates that
Starting point is 00:54:39 this should make proteins cheaper. And that is good for the planet. It's good for human health, it's good for everything. We should be able to make eggs, cheese, milk, all this stuff. Exactly the same as what you get from an animal without the animal. Because the biophysics of a single cell making it is better than the biophysics of a whole animal. Think about a chicken. It grows feathers, it clocks, it walks around, it has energy, it makes heat. So the chicken as a system is not that energy efficient. But a little cell that just eats sugar and it's programmed to do one thing and one thing only. Each sugar makes protein. So the chicken as a system is not that energy efficient, but a little sell that just each sugar and it's programmed to do one thing and one thing only.
Starting point is 00:55:07 Each sugar make protein, each sugar make protein and spit as much of it out. You feel officially can make it way more efficient, exactly. Now we're making great progress, but we're not there yet. We're not a commodity price point. No, why? I'm trying to ask, where is the failure point? There's two failure points. Sorry, I should say there's three.
Starting point is 00:55:23 The first is strain engineering, which is you want to shuffle all the other genes in the organism to stop doing things like growing a bigger cell wall or, you know, taking your time to duplicate. You want to change the genome of the cell to get it to do stuff faster. The second stage is process engineering. When you put that cell in a tank, you're changing the sugar, the methanol, the CO2, the oxygen, the pH, everything about that tank and the condition of the tank has to be adjusted. So there's about 60 variables, and those 60 variables all need to be tuned and tweaked before you optimize the performance of production. The third category is the hardest, which is scale manufacturing. There's
Starting point is 00:55:59 about 100 million liters of bio-manufacturing capacity on Earth today. 95 million liters's owned and operated by companies that use and when I say biomanufacturing capacity I'm talking about big stainless steel tanks you pour water you pour sugar you pour your cells in they make copies and they make your stuff Of that 100 million leaders 95 million is owned and operated by companies 5 million is available for rent of that 5 million leaders companies. Five million is available for rent. Of that five million liters, four million is rented for its entire lifespan by some company, usually a biologic drug company. Because very little of this is being done in food today. So there's only a million liters left to rent. And there's 200 syn bio startups trying to make animal proteins. And
Starting point is 00:56:36 they've all competed for this capacity. So the capacity cost has gone up by about fourfold. But it sounds like the the two, you can overcome with capital, but the first one is really bounded by science. It's more engineering because what you track is kind of what's called the tighter curves, which is grams per liter. And the more experiment you do, the higher that number goes. And so if you can increase your experimental rate. And the few grams that it does produce today, when a normal person tastes it, they're like,
Starting point is 00:57:03 yep, this tastes the same as a wagyu ribeye. No, so remember, I'm talking about proteins, right? I'm not talking about cellular meat. I want to talk about cellular meat last, which is the hardest category, which is what you're talking about. I'm talking about taking that protein and then using it to make a product like a cheese or using it as an egg replacement or that kind of stuff. It's the same protein as what you would get from eggs or milk or what have you. This all just sounds so hard. Well, it's a big problem and it's a lot of money.
Starting point is 00:57:31 So is that a problem? Eggs alone are $200 billion a year. I mean, the methane released from cows is one of the largest contributors to global warming. It's a real problem. Also, we're gonna need to solve this, Jamaat. If we're gonna call a resource constraint. We're gonna colonize Uranus. We're to need to solve this, Jamaat. There's a lot of resources. We're going to colonize Uranus.
Starting point is 00:57:45 We're going to need to get food there. I just asked a question. Like, if you go after the high-emission categories first, do you give yourself room to leave these things because you're doing so much already? Just a question. Animal agriculture emissions are one of the largest and, unfortunately, one of the biggest drivers, because this people's GDP per capita increments, the first thing they spend money on is professional. I get it. I'm saying something different which is if we just
Starting point is 00:58:10 invented better heat pumps, you'd have industrial heating and cooling which represents like almost a third of all greenhouse gas emissions that you get that off and you give yourself a lot of time in space and room and maybe you let the cows roam and belch and burp because the meat just tastes better and you don't have to spend a bunch of time in effort. I don't think it's an ore. I think it's an anchimoth. I think we should be doing all these things.
Starting point is 00:58:32 And I think that I'm a big believer as you guys know in markets. So I'm not a believer in transition for the sake of, you know, carbon saving because people aren't going to pay a premium as we've seen with the kind of alternative meat market. Fifteen dollars. People want cheaper hamburgers. You're not worth it. One cheaper, cheaper, cheaper. So if you could make protein cheaper, it's also a great ROI. You can make money doing this. And the market will buy it because it's cheaper protein. Now the third pet, sorry, I just want to, I just want to hit on this because we keep side-drag it a little bit. The third category is the one that the article was about, which is cellular meat. So cellular meat is where you're trying to make your wagyu or your shrimp or your fish.
Starting point is 00:59:08 You're trying to make cells, not just proteins, but entire cells, and those cells stick together and they look and cook and feel and taste like cellular meat, like muscle, like what you eat when you eat fish or beef or whatever. And the problem there is you're trying to take a cell and cells normally grow on bones and on tissue. And so there's scaffolding and all these systems that hold all the cells together.
Starting point is 00:59:33 And so to get cells to grow in a tank and stick together and replicate without other cells signaling them turns out to be really expensive. There was an executive at Merck, I spoke to a few months ago, and he said, we're going to sell fetal bovine serum, which is basically like this liquid that they get from the fetuses of cows. And this is how cellular meat started. They took a cell from a cow and they put in a tank with Fidel Bovine Serum and the cell started to replicate and duplicate. And then they could take those cells and try and turn them into a beef into a burger and sell it or try it. That was the million dollar burger, if you remember that a couple years ago.
Starting point is 01:00:06 And Feedle Bovine Zero market has gone through the roof because so many companies are trying to make cellular meat. And the Merck exec was like, we're going to sell a billion dollars of Feedle Bovine Zero, and then we're going to sell zero, because no one's going to be able to make money doing this. It's just impossible. You're not going to sell $500 burgers. So the technical challenge there is you have to edit the cells to get them to duplicate.
Starting point is 01:00:25 You have to get them to grow in suspension, meaning in a tank instead of growing on bones and growing next to each other and scaffolding. And then you have to change the feedstock so that you're creating all these other proteins and signaling factors and hormones that you pour into the tank that trigger those cells to grow. Is there any chance that after all this, it actually just tastes slightly different? Or better? It may. Yeah, it actually just tastes slightly different? Or better? It may.
Starting point is 01:00:45 Yeah, it may, but likely not. I mean, let's be honest. These are, you're taking a cow cell or a salmon cell or a chicken cell. No, the reason I take this is that, I don't know, if you, I mean, you don't eat meat, so maybe you don't know this. But depending on where the water that they drink, the actual grass that they eat, the meat does taste different. And that's part of the...
Starting point is 01:01:05 But the cow is massage. I mean, look at the acorn-fed cows that we used to have at poker before our austerity measures. Life was so good in 2021. Well, that's... No, we can't get it anymore. Yeah, I know. We're on a budget. I get it. No, not us. We can't get it anymore because they sell it through one channel. But yeah, like I think that's so good. The variation you're talking about is obviously at an echelon and a class of eating chamauth. It's probably not mainstay. Like, you know, the $30,000 a year McDonald's burger and chicken nugget eater is probably happy to take a
Starting point is 01:01:40 point to disagree with you. Chicken nugget that tastes to me. I disagree with you because if you go into Whole Foods and you actually buy buy a USDA top surloin, there's a certain taste that it has that things that are not USDA don't have. So even at the most basic layer of the food pyramid, you can differentiate on taste based on the same. This is why I'm saying, I think it's just a very complicated,
Starting point is 01:02:03 long drawn out process. And I just wonder if the people that are in these businesses, if they actually love food or not, I understand why they love the science, I get it, and why they would love to save the planet, I get that too. But unless some of these people are also food lovers, they're going to miss, I think, the thing where it all dies anyways. I just want to restate again, for the final time, these are identical cells and identical proteins to what you're getting from the animal.
Starting point is 01:02:29 So they are not like what we talked about in that first category where you're trying to get other stuff to sort of taste like meat. You're literally trying to create the meat and create the protein using these systems. And we're not going to be able to. I'm just trying to tell you that two two pieces of salmon can taste totally different, depending on where it's swam. Right. I guess what I could say is the protein. Yeah, you could probably adjust the conditions in the tank if needed to change the the characteristic. This is my point, like you don't even know where to start. How is it the fucking kelp in the Atlantic Ocean?
Starting point is 01:02:59 Like what do you change it? Look, I don't know what kelp affects on the salmon. I don't know of salmon. But this is my point. It's kelp in the Atlantic Ocean. This is why we pay so much for the acorn fed beef. I get it, but most beef is not kelp from the Atlantic Ocean fed salmon. It's animals grown in very large feed lots fed corn and water.
Starting point is 01:03:17 That's it. Let me just say that again. 90%, 95% of animal protein consumed is cows, pigs, and chickens, grown in feed lots, fed corn and soybeans and water, and that's it. Right. But if you go to different countries and taste the meat that's fed in that exact same way, it tastes different.
Starting point is 01:03:35 So for example, if you go to Argentina, I'm going to be a bit of a... I appreciate what you're saying, but the point I'm trying to make is you can recreate whatever the system is that you're talking about. So I want to just get back to the unit economics. The cost per kilogram or the cost per gram of the protein, we are still many orders of magnitude away on cellular meat. So the problems you're laying out are really down the road problems of optimization. Right now we've got more fundamental problems on how do you actually get this stuff to be cost competitive.
Starting point is 01:04:00 Now fortunately, the tools of CRISPR and since CRISPR cast nine came out 10 years ago, there are now hundreds of variants that are open source, IP-free, royalty-free, and use very broadly and generally, and DNA sequencing costs continue to decline. Those are the two basic tools that are being used by biochemists and engineers to do rapid evolutionary iteration needed to produce the recombinant production of proteins to produce the new cells, to produce the feedstock for those tanks and There's a cost curve that we're trying to get over. It's not happening overnight hundreds of millions of dollars and in several cases billions of dollars have gone into these systems
Starting point is 01:04:34 And it's very likely that these companies may need several more years and several billion dollars We are going to get there the technology is. The rate of progress is a little slower, and it's a little more challenged, I think, than the first round of investors had hoped. But I do think that scientifically and first principles, it is absolutely feasible. It's a function of engineering our way there. To giving Chimath and everyone else that eats burgers and chicken nuggets, everything that they want, hopefully at a lower price. If you put it on the curve of self-driving cars, we have crews doing some automated taxis in a very constrained area in San Francisco,
Starting point is 01:05:09 but we don't have it everywhere. Where do you put this on the curve? That's a great question. So what's happened, by the way, as we've gotten down the cost curve, we are unlocking new markets. So new products are being produced. Existing proteins that come from animals,
Starting point is 01:05:24 there's a good example of a product called PEPSIN. It's extracted from pigs today. It's very expensive. Similar to how we used to make insulin. And we're replacing the sourcing of that product. We replaced insulin, which we used to get from pig splines. We now make it recominantly. We're now replacing PEPSIN. We're replacing the the rennet that's used to make cheese. So as we moved down the cost curve, these high what are called high value proteins are the first to fall. Those markets collapse because we now make them recombinately, they were sorry, they collapse in price because they're now cheaper using recombinant systems instead of taking them from animals. And eventually we'll get to that cost curve where they're ubiquitous for all proteins or for all types of
Starting point is 01:06:01 cells. In the meantime, they're pretty sizable markets to go after. These are multi-billion dollar markets that are getting knocked down. We don't talk about it every day, it doesn't show up in the news, but it's really profound and interesting to see that this technology is working. It's overturning multi-billion dollar markets.
Starting point is 01:06:17 It's making progress, and hopefully it'll get to the point that everything from the chicken nugget to the kelp-fed salmon can have. guys try to be on burger or an impossible burger? I've had it. I've tried them a long time ago, but I've not tried them recently. They're like, it's like eating something mushy that's 60% of average hamburger. It's not worth paying double for certainly for somebody who's a hamburger eater. not worth paying double for certainly for somebody who's a hamburger eater. So, while we were talking, by the way, Amazon's results came out, they crushed it.
Starting point is 01:06:52 earnings per share of 31 cents versus 11. And stock is up 10 percent. 10 percent off hours and it was up 4 percent today, where the insider traders will make that. So, I can't feel about your recession prediction. I'm sticking by it. I think we're still going to recession, but it is an interesting paradox here. So I think there's only a couple of possibilities.
Starting point is 01:07:14 Either tech is sort of a mule, or they forecast down so much. They were so conservative in their forecast thinking we're going to be in a recession that it was easy to beat. Or look, I could be wrong about the recession, but Paul is saying it. And Paul is saying if it's not a recession, it's going to be less than 1% growth. It's going to be around a year to recession. So it's not credible. So I'm not revising my forecast. Well, I think Paul is credible when he's giving us bad news because they're incentive is always to fluff it up and make it sound better than it is. So when he's telling you things look bad, maybe they're looking really bad. I don't know, man.
Starting point is 01:07:53 But look, it's a tale of two cities right now. I mean, the big tech company seems to be doing really well. So it's definitely a paradox. Yeah. All right, everybody. Well, the whole RFK thing. Okay. That's a good topic. Yeah, great topic. Go ahead. I think we should tell people like what he's about. Where are all yours?
Starting point is 01:08:10 I think he gave a terrific announcement speech. Okay. And it just to give you some background for the younger viewers who may not know. So Robert F. Kennedy has father ran for the Democratic nomination in 1968 after his brother John John F. Kennedy, had been president, it was assassinated as we know, and they're early 1960s. What happened is, at this time, before the 1968 election, Linda B. Johnson was the incumbent Democratic president, and everyone thought that he'd be the party's nominee, and he was going to get reelected, and he was brought down by an extremely unpopular war, the Vietnam War. And it was RFK Jr.'s father, who was a great critic of the Vietnam War, and he was brought down by an extremely unpopular war the Vietnam war and it was our f.k.
Starting point is 01:08:45 juniors father who was a great critic of the Vietnam war and he ran for the democratic nomination and I think that he very likely would have gotten it on the night that he won the California primary he was assassinated by sir hand sir hand right yeah if you go back and look at the things that he was saying in that campaign, he really was saying a lot of beautiful things that are in his son's ad that I think would be worth playing here. But I think you have maybe the set up for a similar situation here. You've got an incumbent Democratic president who is sort of not that popular. He's sort of old and out of it and incoherent.
Starting point is 01:09:21 He's presiding over a war that is rapidly becoming a debacle. You don't hear so much about the spring counteroffensive anymore. These new Pentagon papers that were leaked show that the Ukrainian casualties are at least five times greater than they've been publicly admitting. It looks like Russia's certainly not losing the war. They're way they used to be. They've captured 90% of Bokma, which has been the most violent bloody battle of the war. And Biden at this point has no strategy to bring that to an end. In fact, he's rejected multiple attempts at a peace deal, and so now it looks like it's the Chinese who are in the driver's seat potentially putting together
Starting point is 01:09:56 some sort of diplomatic settlement. So I think, listen, if the economy ends up going into a session, and this war ends up becoming the fiasco that's increasingly looking like you could have a set up like nineteen sixty eight where people are wondering why the hell is this guy our nominee and let me tell you rf cage you years already pulling at nineteen percent which i think it's pretty good considering he just came out of the gate and people don't even know the substance of this campaign yet marion williamson's at nine percent so she dropped out, you'd be at 28% for the alternative. And I think he could go up from here. And I think if you if you watched the speech he gave, I thought there was a lot of really beautiful sentiments in there. He said that Biden
Starting point is 01:10:37 is made Ukraine a pawn and a geopolitical battle that has put the flower of Ukraine's youth into an abattoir of death in order to exhaust Russia. He channeled America's anti-war traditions, he quoted John Quincy Adams, that America should not go abroad in search of monsters to destroy. He quoted Martin Luther King Jr. There is a direct link between poverty and violence and oppression at home and war abroad. He talked about the role of the CIA during his uncle's administration, where he said that John F. Kennedy eventually realized that the purpose of the CIA had become to
Starting point is 01:11:13 create a steady pipeline of wars to feed the military industrial complex. And he talks about how JFK came to distrust the CIA and realized that that it was lying to him and the biggest appallion of his speech was when he quoted jfk approvingly saying that he wanted to take the cia and shattered into a thousand pieces and scattered to the winds and this very same week that he gave the speech we found out that five former cia directors have participated in a giant hoax on the american people by claiming that this
Starting point is 01:11:44 hunter-biden story was Russian disinformation they knew it was not had participated in a giant hoax on the American people by claiming that this Hunter Biden's story was Russian disinformation. They knew it was not. They knew it was not. The information on the hard drive was real. It showed that Hunter Biden received multi-million dollar payments from foreign governments, including China and Ukraine, okay? And regardless of what you think of that story, it should not have been suppressed by social media, and it certainly should not have been suppressed in a siop by 51 former intelligence officials, including five former directors of the CIA. And if that's the way they're going to behave, if they're going to meddle in American politics that way, I think we do need to start over.
Starting point is 01:12:20 We do need to ask what's going on with the security state. They're not supposed to be meddling in American politics that way So I think if this is the way they're gonna act I say shatter away scatter that thing into a thousand pieces. Hey Catholic. I'll vote for him And he's called out the insanity of COVID lockdowns and Man, that's the thing that he's I guess that's the big controversial season anti He's an anti-vaxxer. I guess that's the one thing they're trying to position him as. And he does a little bit of conspiracy theories.
Starting point is 01:12:50 So listen, if you go back and look at his record, he was an environmental activist, most of his career. He did the Warton project in New York, but they basically bought the land along the Hudson. I remember I was at some events for it. They wanted to clean the Hudson up. And they just blocked the land and people donated the land and they bought it, they raised money. And the Hudson today has like, it's flourishing amazingly.
Starting point is 01:13:14 And he's directly responsible for that. He was a big critic of the way that corporate greed could lead certain big companies to engage in environmental pollution. And at a certain point, he realized that big pharma had a similar incentive. Now, I don't know if he was right about those vaccines, but I do know that he's right in the case of COVID.
Starting point is 01:13:30 They had an incentive to push this dubious, uh, uh, get your information shot on us so that we get boosted as Zillian times. And he's right about that. He was right about the fact that this should never have been mandated. We shouldn't have the lockdowns. And you know what? In his nomination speech or his declaration,
Starting point is 01:13:46 the word vaccine was only mentioned once. So this is not what his campaign is about. I look forward to having him on. Yeah, and to be honest, I mean, look at all the other things that were deemed to be conspiracy theories that ended up being true. Oh yeah, I mean, this is monster.
Starting point is 01:14:01 Yeah, not that. You go either way. I could be a little sorry. Or it could be embarrassing. Let me ask you this, Axe, if it was him versus Trump, what do you vote for? Well, I'm going to reserve. Okay. I'm a reserve. Okay, versus Trump sex. I'm not going to take position on the general yet, but in the Democratic primary, I'm definitely endorsing RFK junior in the North Democratic primary. Okay. I'm forwarding the democratic primary. I will.
Starting point is 01:14:25 I would if I could. I'll do an event for him. All right, everybody. All the amazing people who got together for the episode, the 125, unbelievable, over 40 or 50 of them, Ray, great job. Shout out to Ray. Shout out to Ray.
Starting point is 01:14:38 I dialed into a bunch of them and I think, oh, it's great. Europe and I don't know all over the place. No one got robbed or mugged or bear sprains. Hopefully, I don't know, all over the place. No one got robbed or mugged or bear sprites. Hopefully, I don't know if they did any in San Francisco. There's no bear sprains in San. So that's good. They'd have been turned up to some marina.
Starting point is 01:14:53 Marina. All right. Four of the Sultan of science, the dictator himself, and the mouthfeel. The mouthfeel. And, right now, I am the world's greatest moderator. We'll see you next time, everybody. The... Melfield. Melfield. Melfield. And... Rainman. I am.
Starting point is 01:15:07 The world's greatest moderating. We'll see you next time, everybody. Love you boys. Bye-bye. Bye-bye. We'll let your winners ride. Rainman, David Sack. I'm going on a win.
Starting point is 01:15:20 And it said we open-source it to the fans and they've just gone crazy with it. I'm the U.S S I S Queen of Kenwa I'm going all in What? What? What are you trying? I'm going all in
Starting point is 01:15:32 Besties are gone I'm going through That's my dog taking a wish to drive away Sixx We're going to die Oh man, my ham is the actual meat We should all just get a room and just have one big hug or two because they're all just like this sexual tension but we just need to release that house.
Starting point is 01:15:51 What, you're the beef! What, you're the beer beef! Beef, what? Let's get a beer. We need to get my cheese already. I'm going on, Leigh! I'm going all it.

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