Brain Soda Podcast - Episode 51 - Blue Methenger RNA Vaccines

Episode Date: February 10, 2024

On this week's episode we're talking about the critically acclaimed television series Breaking Bad, and an overview of the various types of vaccines!

We're the podcast who knocks. Ah, brain soda. It's the Brain Soda Podcast. I, as always, am your host Kyle joined by my co-host and cohort Brad. How's it going? And today we have a special guest in our good friend Matt. Yeah. Hey how's it going? It's good to have you on man it's been a long time. How's everything been going out that way? Oh it's been alright. A lot of strange weather you know. No snow. Yeah. But you flooded out the whole ocean into your city, right? Oh, yeah. Yeah, the whole river full ice just flooded into the

streets. It was a good time. That's crazy, man. Well, we hope everybody's all right out there for all of our listeners in Maine. But with that, today, we're going to be talking about vaccines, but first math. No Do you guys like math? Well, what about like some from Arizona a little blue action from out west? I don't get out west very often. Unfortunately, you know, but you do a lot of math, right? That's the kicker here is the math's gotta be How do you feel about science? How do you always feel about science?

No, that actually I love, yes, of course. I'm not saying the science. Item as well, but today we're gonna be talking about Breaking Bad. We're gonna be talking about Breaking Bad proper, so we're not gonna be discussing El Camino nor Better Call Saul. And I wanna start this topic off unfortunately

pulling off a band-aid for myself because in episode 36 I misspoke Brian Cranston the large topic for our subject here today. He actually didn't play Zordon, he did in the film and it was my personal recollection that misunderstood that. He was talking on Conan O'Brien about appearing in the 2017 Power Rangers film and he had done some voice over work for Power Rangers but he was never Zordon himself. Actually the way I learned it was the guy who played Zordon like totally got gypped and had like two days pay for seven years of television we were entertained by. Well, I mean, you still played it though.

So like you're someone right. I understand though. Yeah, but it's crazy. Yeah, but I definitely did later on be like, oh, my bad guy I've never heard of. My bad. That's good for the correction though. Yeah, I definitely wanted to make the point

to make that correction, but I feel like that is actually a really important start at this point in Brian Cranston's career He's kind of just doing bit rolls The guy had made appearances on things like Seinfeld and mighty morphing power rangers, which we've both discussed before Other shows as well like murder she wrote and a little show that I think we're gonna talk about actually kind of soon called The X-Files. A writer on that show though was a guy named Vince Gill and that guy went on to write Breaking Bad. Now, I wanna make that point is that like The X-Files was kind of running to the end of its run and at the same time like a flower that just suddenly decided to bloom. Brian Cranston kind of rose

through the ranks in television because Malcolm in the middle hits, right? We're talking like 99 early 2000 here. I will tell you the one bit where he has to change a light bulb and then he like needs to go get his toolbox and then realizes that his car's tires low. So he has to do that and then realizes this thing's bad and he has to do that. That is the epitome of being a homeowner and a father. And like countless other things. I feel like Brian Cranston's role as Hal in Malcolm in the Middle like brought him to the dance absolutely but like even if that were to be the only thing you ever knew Brian Cranston for it is kind of like a tour de force like he really is an actor in that show who makes you feel anything right and everything like you said in a

typical day-to-day nuanced explanation of how I go to fix one thing and I end up fixing five others because that's the state of you know the world I guess right you can relate to that there's a lot of, you know, the world, I guess, right? You can relate to that. There's a lot of actors who can't make you feel or relate to that in the way that Brian Cranston or an actor of that caliber can. And I feel like that's exactly why he was chosen to be Walter White.

Like before we get into Breaking Bad, is there any conspiracy theories of there being a world connected where Malcolm in the middle and Breaking Bad are connected. There's tons of fan theories about Hal like I don't remember the mother's name and Malcolm in the middle but yeah like Hal faked his death and left the kids and you know resta but that's that's be fair about that and the character narrative If how were to have done that man the fact that this guy's midlife crisis Results in him being a high-end drug dealer Kind of makes sense because like when you be disappointed if you threw your whole life away for something better

And then it completely f***ed on you and you have like a son with cerebral palsy, you're dirt a***** poor and disrespected, although like you could have been the leader of a high-end f***ing chemical company 20 years ago. Like it is really such a raw f***ing hand that Walter White has dealt. And I feel like the time in which this show is coming out, the housing market crash, the great recession. What year is it that actually comes out? In 2008, so many American families are desperate, hurting and in a place where they can relate to this story oh so well, even if realistically the whole time you're rooting for Walt, you're questioning your morals for doing so.

See the connection there. Yeah, like, well, at that point we were like, what, graduating high school and stuff. So like, really, I mean, we had a different experience than him. Absolutely. But well, kind of like Jesse though, in a way, Jesse, I guess, would be a good, we were the Jesse's of that time. Right. Yeah. And that is really like one of the things I think that it kind of shows, right? Like with crime comes desperation. And with Walt, you see this guy who is a chemist, literally like felt like he had a raw hand and a raw deal. Seize this bust and the amount of money that meth can make and the low level chemistry

that it is. And follows out with his brother-in-law sees a bust happen and then recruits Jesse Pinkman and one of the funniest things about this show this first season is kind of notably Slow and I air quote the term slow because yes even if you don't find these six episodes to be like breakneck speed or these six episodes to be like breakneck speed or terribly interesting across the 45 minutes or whatever it is that any episode entails time wise. They really do build upon what you're going to see

going forward and build such a great base for it to happen and it's like detrimental to miss out on. But I think one of the funniest anecdotes about this point in time in the show is that originally Jesmy Pinkman was supposed to die and fortunately the writer's strike prevented that. Yes, I heard about that. That's crazy. So they completely changed the series.

Jesse Pinkman was intended to die in the original script? He was. And the thing is as well is that like Aaron Paul is delivering such an amazing performance in these early seasons that like they kind is delivering such an amazing performance in these early seasons that like they kind of knew they didn't want to kill them off. They may have found a way to rewrite it or work it back in or something like that. But thankfully the writer strike happened and they're like, oh, well, we got it.

Wrap it up short guys. But Justin doesn't have to die. You know, they didn't have much of a choice. I mean, he was he was such a big focus in the series, you know, they didn't have much of a choice. I mean he was he was such a big focus in the series You know, but I feel like that first season gives you so many different cues Right like the way that it plays out for Walt to go through the events of season one and have them constantly Kind of replaying in the foreground and those cold opens leads into like I would argue some of the most like those cold opens leads into like I would argue some of the most like thematically memorable stuff with the plane crash later on and even beyond that I think the most common through line you get through this season is when later on Walt is trying to decide if he's even capable of taking

this man's life and because of the actions that this new Walter White has kind of laid out like he has to. And from this point forward, there always feels to be the invisible hand of fate pushing circumstances and situations into Walt's way, hanging them over his head or using them to pull him back and constantly. Is it faders of himself though? Because I know a lot of times he kind of does that

shit to himself. Because you have made mistakes, poor decisions, out and out evils at times for Walt. Karma, maybe the better term, runs back around full circle to find those instances. Again, around full circle to find those instances. Again, with the plane crash stuff, because Walt doesn't act when Jesse's girlfriend's dying, because Jesse is potentially blackmailing him to get out, or out and out just trying to leave, he lets her die. And the dad who's been sober with her,

and that's his child, and only that but that's like, you know, kind of his accountability buddy and recovery to a certain extent. She's died. He's an air traffic controller. He's so traumatized. He makes a simple mistake at work. And one of the most devastating things in the state of Arizona happens essentially because of Walt's immediate non-action. Yeah, because non-action is action. You know, and like that's, you're right, because like sometimes it's not necessarily, because he does do some crazy stuff. Like it's into the first season. Did he blow up the drug dealers in the first season? I'm

trying to remember. Yeah, he makes that explosive, but it's not like, like I don't think he blows up the whole building He blows it up to be like by stuff that explodes when you throw it Yeah, yeah something like that is crazy, but it was pre-meditated like he had that on hand Yeah, I mean he put himself in the situation, you know because it was like a Absolutely, he was always intelligent enough to get him out of it for the most part. Exactly. But he was also always so big and brazen to open his big mouth and put his foot in it at times.

In that exact situation, I believe you're referencing Brad. In his early dealings with Tuko, he knows this guy's nobody he may have messed with. And literally it is his big foray into being a bad person. He looks at Tuko, this guy who will beat and kill anybody who steps across him the wrong way. He's a complete loose cannon. And he goes, I'll get you four pounds instead of two pounds. And even later on, by the time he kills Gustav, and he's kind of embracing that Heisenberg role before everything topples in on itself. He's so brazen and hardcore. He's walking up to drug dealers and being like,

you're aping off me at every step of the way. But we're the best meth cookers in the country. Say my name, you know what I mean? Like he's walking around acting like he's a pimp, stepping out of a Cadillac, about to slap somebody for some money. More than he's acting like the sheepish quiet timid School teacher that right walk into the room and meet at the beginning of the series you apply that to reality though

Like how's that gonna fly? I think breaking bad is a realistic look to a extremity in gravity, right? Like it is taken to the 10th degree and this sheepish chemistry teacher who's really nice, his son has cerebral palsy. Like you throw out every sympathetic card. I could see something like that happening.

I mean, yes, obviously it's dramatized, but like I could see some person that knows it's going in and starting to create like some crazy cuz I mean a lot of people probably do that You know, but right absolutely as a matter of fact a really good parallel to Walter White in this show is the character of Gale Gale again, it's like a not sheepish and timid, but he is like he almost seems like a really well-behaved choir boy Like a really smart well-behaved choir boy, right? Another one, well, sorry. There's this book that I hear recommended all the time called The Alchemist,

and it's an older book, but I searched it one time, and the book that I found was about this drug dealer that was like a Walter Wright type situation you know. Well there is a real Walter White. There is a guy, yeah. Would I know but like it was just another star, it was an older one and I'm reading this book and I'm like why is this so it's such an acclaimed book and then you know years later I thought it was a different book but. Dexter too. I mean working under your cop siblings nose, doing your profession to do... Right. Yeah. People with the know-how often know how to exploit

that avenue or whatever it may be, right? But you can make a very good argument that karmically the reason why Walter White doesn't and will never have those things is because when he's put against the wall, this is what Walter White does. But in reality, a lot of times I think the midlife crisis or the end of life crisis as Walt gets his cancer diagnosis is often a Ferrari. You know, it's not exactly let's become a drug kingpin. It's let me divorce my wife and hire this chick with big tits. I think part of what makes this show so important to the time, so influential, so critically acclaimed is because it is a large scale morality scale. And for a lot of people that means a lot when we lay it out

and get to view the lives of the characters that we maybe see some of ourselves in. Yeah. I mean, because it really is like it's a very, it's not just like, you know, we've talked a lot about Walter White, you know, but there is like, there's a lot of different characters that you can kind of see yourself in because it's absolutely like how you said it is very reality like you know because what I mean is like why he doesn't have a Ferrari and you know a new wife and everything like they show like he had a launderous money right you can't just have millions of literal dollars right what are you gonna do with that you

gotta launder it right well, but even well before the events of Breaking Bad, when we're looking at the formation of that chemical company, that like- True, true. He later has to lie and say he got money from those people to pay for cancer treatments that keeps cooking meth to fill the obligation of us, right? Yeah, that's very true.

It all starts in a place of him, yeah. Maybe the s*** doesn't always fling onto the fan and onto him. It ultimately does very heavily on, I would say the second most important person to show in Jesse, you're seeing Mike and you're seeing Saul and you're seeing Gus and Hank. I feel like with Mike and Saul, obviously they get a spin off of their own. We'll probably talk more about them at that point, but God, those are good black mirrors and the kind of dark humor you get with Saul

and the kind of like gruff textured story that Mike has laid out. I feel like those things are interesting enough to juxtapose with Jesse's story, with Walt's story. But when you get to like Gus, and you see just Gus's story, it is a really amazingly laid out tale that, man, dude, there's just so many different elements of this show. Gus, right? You're talking the chicken store. I'm sure he was in a bunch of stuff. I'm actually, I know he was, because I've seen like older movies now with him, but man, he blew up play. And he is

an amazing actor. Like, well, he just plays that bad guy. So good. Seriously. I mean, he's a guy who's definitely been typecast for sure. And I feel like I feel bad that that's happened to that guy to a certain extent. And I feel like unfortunately you don't see Aaron Paul like for the amazing performance that you get from Jesse Pinkman. You've seen Aaron Paul and like a number of things and he always did as well. But like from where he was around the time that this show gets it's like 58 Emmy nominations and 13 critic choice awards nominations like you don't see him in anything anymore. And maybe that's his own doing maybe he's

kind of stuffed away from acting a little bit and stuff like that but yeah like these five seasons I definitely suggest to anybody I feel like it's super informative to what television overall is today what storytelling I think is kind of expected to be overall today. And like, honestly, man, when we talk about streaming in and of itself, I feel like this is one of the shows that really helped push it into the foreground

because while AMC was top dog in it, in the cable realm with Mad Men, Walking Dead and this, Netflix also was gaining subscribers, footholds, and ushering in a future of how we're gonna consume media with Breaking Bad as one of its top tier choices on the platform. Yeah, I always forget that. It's a Netflix show.

It's not a Netflix show. Yes, that exactly. That's true. See, because of that, it's so ingrained in my mind that it's a Netflix show But it's not a Netflix show. It's AMC. You're right. Yeah, it's crazy There is some slow parts like you said it was season one like I did I struggled to get through that season It actually took me a few times. I think everybody does. Yeah. Yeah, I think the hype is what gets me Exactly. That's the thing. I'm like, I just got to get through this same thing like with the expense

I know I just talked about that, but the first season is not... I mean, it is good. It's definitely good, but I think it gets better as it goes on. There's lots of shows like that. And it's lower stakes. Right. It's way lower stakes. For sure. You know, though, like one thing that is crazy about Breaking Bad, I want to say like super scientifically accurate, but they were pretty scientifically accurate with a lot of the stuff. Right, you know. More, yeah, more consistent than in consistent. Exactly.

Typically. Well, Mythbusters did a whole episode on like Breaking Bad and testing, you know. Exactly. Yeah, well, funny thing is that he was almost like doing stuff like on a pharmaceutical level, right? Like he did at the end, right? Oh, absolutely.

In an industrial level. Yeah, versus like at the beginning, you know, he's like, end, right? Oh, absolutely. In an industrial level. Yeah. Versus like at the beginning, you know, he's like, no, we're not putting that chili powder or whatever, right? Yeah, yeah. Like it's just kind of funny to me is that there's a lot of people, this isn't going to be the main subject of what I'm about to talk about, but that will put crazy random drugs that are made by who knows who and for who knows where and then are like, nope, I won't take a vaccine.

Yeah. Yeah. We are going to touch on COVID vaccines, but I just wanted to talk about vaccines as a whole because there's a lot of them that are tried and true that don't put strings in your veins or don't hurt you or anything like that. We're going to be talking about what vaccines are, the different types of vaccines and a little bit of history around them towards the end.

But a vaccine, people think that like, I think it's just like, there's one type of vaccine. I think with now with COVID, they kind of, you know, open up people's minds a little bit more about the different vaccines. But still, essentially though, to put it in as simplest terms, it's a type of medicine that's made from a very small amounts of weak or dead germs.

So most of the time there's not even anything living in it. It's just it's dead DNA or different antigens or something like that that cause our bodies to react to it and then create antibodies against this disease or germ or whatever it is, you know. And a germ could be a bacteria or a virus or even toxins to it. So vaccines prepare your body to be able to identify and respond and to fight the pathogen a lot faster than if you were to just, you know, get it naturally. If you were to, even if you, the thing is that even if you get sickness naturally and build up immunity to it, you're still not going to be able to fight it as quickly as if

you were to have a vaccine against it. And I hate to bring up COVID a bunch because this, you know, especially because like I'm so dealt with COVID, like right, it's 2024 now. Right. Society has been over COVID, right, agreed. You know, some people are saying, well, I got COVID, you know? And so I don't need a vaccine now. Like, well, no, the vaccine's different. Like it's a different type of buildup to your body.

Not saying that you need to get it, you know? So really it's called immunization though. Like that is actually, like that's the process of becoming immune or protected against a disease, right? Of getting vaccinated is the process of becoming immune or protected against a disease. Getting vaccinated is the process of being immunized. They're created in many different ways. We'll get into in a minute all the different types of vaccines.

There's actually, I think, six of them. But scientists use a number of different methods to discover and produce them too. There's so many different pathways to vaccines to to like classify them saying all of them are bad is kind of like ridiculous really because there's kind of like the dies really like we were talking about the other day. It's almost as if there was some arbitrary reason for these people to like have a problem with them. Exactly and like I mean don't get me wrong there was a time when vaccines first started coming out and getting big, like we didn't treat them

as serious as we do now. And there was some that really people up. Don't get me wrong, like especially babies and stuff. I mean, we're talking the 1950s and like 60s, 70s. Like, you know, like, I mean, yeah, like recently. But that was like when the FDA and stuff was first getting for him, you know, like that was a lot of that stuff a part of the reasons why we have things like that today, right? Exactly like it's so much more strenuous to get a vaccination approved now

You know like it's a lot different so the way that scientists just discover new vaccines, right? They have to consider how your immune system responds to this germ. Like bacteria and viruses, they work in different ways, right? Bacteria kind of like just attack yourselves versus viruses that kind of like use yourselves, hijack yourselves, DNA essentially to replicate more of themselves, right? So they have to look at that. I was going to say they kind of like body snatcher it, don't they? They like adopt or co-opt yourselves. They hijack your replication factory. Yeah, like they like take your DNA and say, hey make more of us instead of more of you now. Essentially, yeah. Also like who the target for the vaccination is because

you know like sometimes vaccines are only for older people or younger people or people with a specific you know. Compromise. Yeah, you know or like with STIs and stuff like that. You know like those, you know. Amino compromise. Yeah, you know, or like with STIs and stuff like that, you know, like those types, you know, like those are, that's a completely different vaccination than other types of, you know, vaccines, things like that. Like the flu vaccine, like I want to get it every year. And I unfortunately don't, like an idiot, like,

cause like, and I get the flu every single year, you know. Especially now with my kid in school, you know, I was just so over all of this. I was like, let's just get back to society, give me the stupid jab. I was stepping in the line. So you just gave in to the band room? I mean, essentially, yeah.

You just let them kick you with 5G? Well, it's not even that. You just let them crack you? It's because I understand the science behind things. And I'm not- You mean you read some books and figured out some. Speaking of which, let's talk about the first vaccines because this I would not do, right? This time with the history of them. The first vaccines were actually against smallpox and

they began because people realized that if someone contracted cowpox, which was like a lesser sickness than smallpox, that after that they would not end up getting smallpox, right, they were immune to it. So some of the more observant people began infecting themselves with cowpox, you know, to help prevent themselves from getting the smallpox. They're in the same like class of viruses, right?

And they did this by cutting open the pox's and then like putting that infected blood and pus into a cut of their own, you know, like they cut themselves too. Right. I mean, you know, teach their own. Yeah. Well, I mean, like think about it. It's like, do that or die. Right? I would, you know, back in the day, I would do that. Yeah. I mean, this is probably closer to the times of the humors and things like that. So like bloodletting and things like that are not abnormal. Yes, this is like 17, 800s. B, when you look at the realistic application

of something just like this today, it's blood transfusions and blood donation, like plasma and stuff like that, right? Yeah, it's just done in the hospital. You're using uncoagulated materials to end up ensuring that you're able to build antibodies for sicknesses. Yeah, the Chinese might have had a better way of doing it. Like I guess a better way of doing medically. Maybe not the better way of doing it, like if you think about it, but they would cut up these dried up like oozes and scabs of

cowpox and then they would snort it and because of snorting it, your body it builds immune through your nose nose like that's usually your body's like a defense system right there right there's a filter right there yeah it's a little bit better like you can like I guess your body like reacts to it better right then like cutting open because and also because cutting yourself open is dangerous for like other infections like right they didn't know sterility back then. They just knew that, you know, cow boxes were related. But still, just starting a scam, I don't know. So everybody just go to the doctor,

don't go snorting cow scabs. We have to wait around that now. And that's the thing, yeah, like chicken pox, this is related to them. All these pox's are related. There's vaccine, like this is one of them. All these pox's are related. There's vaccine, like this is one of the vaccines that you should definitely get. I don't know why you would not get this. It's a no brainer to me. Yeah. Now this, I was going to say, like you said, it kind of is

universal. It covers several different pox forms and things like that. But typically, these are all like lesions. Lesions, yeah. Yeah. Right. These are all lesion as sicknesses. So are there like things Comparable to it that would be in this wheelhouse. We wouldn't think of like shingles. Well, that is chicken pox shingles is chicken That's what I was gonna say shingles is like the man's another form, right? Mm-hmm, and if I'm not mistaken like all these are related related to herpes too. Yeah, I mean, yeah, but I'm not a doctor. I say this. No, you're right though. Yeah, but let's get into the different types of vaccines though now. There's multiple types, like I said, the inactivated vaccines,

there's live attenuated vaccines, messenger RNA vaccines, or mRNA vaccines, that's the COVID one, and then there's a group of them called the subunit, recombinant, polysaccharide and conjugate vaccines. They're just all kind of, they're just a type. We'll get into it. Conjugal? Conjugal. Oh, gosh. They're like going a different way.

There's toxoid vaccines. And then the last one is viral vector vaccines. So the first one, inactivated vaccines are some of the most common ones that you see. And they work by exposing your body to a killed version of the germ that causes the disease. Right? So like, this is the one where it's just like they kill the germ. And then from that, just you being exposed to that germ, even if dead, your body makes builds antibodies to it. And they usually don't really provide a strong immunity

because it's a killed version, right? And because of that, there needs to be multiple rounds of this shot. And some of these that are common are like the hepatitis A shot or the flu vaccine, polio vaccine. And rabies too, actually is an inactivated one. So you have to take these either season or be. And you'll leave.

Yeah, or some of them, polio, for instance, you take it enough times, you're good. Or even rabies, that one I guess you don't have to take over and over and over again if you ever get bit. But you don't have to take it, I think, two or three times. It's a multi-shot thing, it's not a one or not. Right, rounds. Rounds is really the most important aspect to it because it just can't be done with one simple inoculation. Yeah. There are a few rounds exactly. Like really the flu is the only one

that's like every year. I think like constantly be like updating these and testing for like new versions of these. Well, sometimes they do. Well, now you do. Yeah, I was gonna say, for the polio one, they didn't have to. Now you do. You didn't have to with measles, mumps, and rebella,

and now you do. It's a time to in a minute, yes, exactly. Like actually measles, I've just been reading. That, yeah. Which was the next vaccine, which, or type of vaccine, which is the live attenuated vaccines. And they actually carry living forms of the germ, all right? So, you know, there's living forms of it,

but they're weakened or what's called attenuated. And that means that they're not actually gonna infect you. They're still alive, but they've been weakened to a point where they're not gonna hurt you in any way. And your body can easily fight them back. It just makes them present so that you, your body starts to slowly develop an immunity. So like you would have to do that many times.

Actually, it's the opposite because they're living. It actually promotes a stronger immune response. And because of that, it creates a longer lasting immunity to it. Yeah. Now how exactly is it that you essentially like hobble these things? That's the thing I don't get. I didn't look that up.

I probably wanted this to either heat it or they genetically modify it. That's probably a big thing too, is genetically modifying it to where they don't even have the things. Right. So that way it just can't replicate. Exactly. Yeah. Okay. Things like that or like exposed to a certain chemical where like, you know, cleaves off something or something like that. You know, like in, and the reason why I ask is because these are kind of common as well. Right. This is not the, the M. R.

And these are really, yeah, yeah. They're really big ones. So, so that technology had to be developed before the 50s, maybe even before the 20s. So it's one of the earlier ones for sure. Right. Yeah. And so it just seems like, wow, like, how did you have the know how and capability to go in and essentially like, neutralize this theoretically, like deadly virus to be able to minimize it.

I really do think a lot of it is, like back in the day, I don't know, I didn't look up what it was exactly, but I bet a lot of it was heating it or freezing it or something like that. Right, okay. You know, we're just damaged the virus or the bacteria enough.

Like the cells living, but it's not fucking. Yes, where it can. Where your body can fight it back before it can get a hold you know and like because like well nowadays you know I bet you it's different but because like one or two doses of these will really transmit like a lifetime protection from these diseases in a lot of cases um and some of them like you've been saying like the mmr one that's a live attenuated one, these because they're live attenuated,

some people with medical conditions and stuff are advised not to take them, because like weakened immune systems and things like that, yes, yes. Immunocompromised, right, exactly. Your body really isn't in the place to try to fight off in general. Don't introduce to try to find it off.

Yes, and like most try to find it off. Yes. And like, most of the time, it's recommended to talk to your doctor. Like they say, right, talk to your doctor before, you know, asking for taking this blah, blah, blah. But the thing is that like, you get it from your doctor, most of all these vaccines, at least live attenuated, right, are coming from a doctor's office. So talk to your doctor before you, your doctor gives you the vaccination, I guess. I was gonna say, even if you're getting it at your local health department

or something like that, you know what I mean? Like usually those things are- Yeah, they're gonna ask you questions. Right, exactly, usually. Yeah, if you're taking it to something that's like, yeah, if you're immunocompromised, they'll say, hey, are you immunocompromised before they jab you at this thing?

Consult with your doctor, although like a broad term to kind of cover the a** of a lot of pharmaceutical companies is realistically just always a good catch-all. Some other live attenuated ones though, are like the smallpox and chickenpox are live attenuated ones and yellow fever too, which is big in the Southern Hemisphere and all that. But yeah, so to continue on to the next one,

and this is the one that caused all this controversy is the mRNA vaccines. And it's the newest vaccination technology. And it obviously has been made famous by COVID-19. COVID-19. Kenneth Copeland. Represent. Did I get it?

Did I get it on time? Okay. Yes. I like trying to hit the button as soon as you did it. And I get it? Did I get it on time? Okay. Yes. I like trying to hit the button as soon as you did it. And I was like, damn it. But this, even though it's a new technology, this technology has actually been studied for decades.

And like, so like it's been this idea to use MRNA, which we've talked about before in our cell episode, right? So we know it's what goes from the nucleus out, right? This is what COVID virus hijacks. So by being able to send this vaccination out, it will hijack the hijacker, essentially, right? Right, right. And well, the mRNA is the COVID, right? The COVID is an mRNA

molecules. But the thing like this technology though has been studied for decades. And really, it just like, we got funding, like big time during COVID because like, hey, we can do this with, you know, this vaccination type, we can, we can fix COVID. Right. Right. It was quite important to get that out. Yeah, they threw unlimited money at it, essentially. Humans can do anything if we throw unlimited money at it. What it does is, like I said, makes proteins. Because of the technology,

like they can quickly make these vaccines because they just look at the RNA of this virus and they go, oh, okay, it's got this RNA. Boom, let's make this one. They can like like print it essentially. I'm simplifying this way, but it's a lot easier to develop. There's a clutch song about RNA. So the next one is the subunit, the recombinant, polysaccharide, and the conjugate vaccines. Why I group them together is because they attack specific pieces of the germ that elicit them in response. So like if it's the subunit of the germ, they have like different molecules, right,

on the outside of the cell walls, the bacteria do, or different sugars, or just like different things, markers, I guess, on the cell walls that are used to attack our bodies. And through that, we make a vaccine that attacks that thing so that it can't deactivate it, essentially, right? So it's not dangerous. So it just attacks the bad cells offensive system? Yeah, exactly.

It's attacking its weapon. Yeah, that's I guess the perfect way of putting it. So these things, some of these vaccines are hepatitis B, HPV. The, you know, HPV actually is kind of a recent new one, right? Or whooping cough too, or the D tap, or part of the D tap shot whooping cough. That is one that's very important to get very safe and everything. Also pneumococcal diseases and meningococcal like meningitis diseases and shingles too. The next one is a toxin vaccines and this is targeting toxins made by the germ and tetanus is the big one that really is a toxin vaccine. Also diphtheria too.

Diphtheria is like, you know, the, I think it's like a diarrhea, essentially disease, right? When you drink bad water. And tetanus shots hurt too. I hate them. Yeah, well, the Dtap, if I'm not mistaken, it's multiple ones. So it's kind of cool because the T, I think it is tetanus

and DTAP. And from that, there's different vaccines in there. I didn't know there was different types of vaccines in that. I thought it was all the same type of vaccine. Or I knew it was different type of vaccines, but yeah. And that's a very important vaccination for your children to have. Oh, absolutely. Yeah.

It's important for you to get like, you're supposed to get a tetanus shot every 10 years anyway. Yep, exactly. Yep. Before we had our kids, we went and got our DTAP because I think it's 15, which we become an adult. But yeah, there's one last vaccine called the viral vector vaccines. And it's still relatively new. It's not as new as the mRNA ones, but it has been used to fight against a few diseases. And what it does is it's a modified version of a different virus. So like, you know, it's like a virus that's not so dangerous to us or not dangerous at all to us that they genetically modify to have the genes or the markers of another virus. And so your body responds to this virus, not it doesn't hurt you at all. And then now you're immune to this new one. And that's really like a good way, you know,

right to help. Yeah. Right. But it's, you know, it's a GMO though. Oh, no, no GMO man. It's like gluten free. And because of the way it's made though, you can target a bunch of diseases. So you can make this like one like innocuous virus have like a bunch of different markers for like 10 different viruses instead, you know? So yeah, it's actually pretty promising if we can like really nail down this technology. Right. Yeah, a universal vaccine that worked for everything

would be amazing. There hasn't been like a multiple one yet, but there has been vaccinations made for COVID with this, Ebola, measles and a Dino virus too. Actually like they're still working, they're the working on ones for HIV, the flu and Zika virus too with this one. So like this is promising man, this and that RNA one.

Yeah, it was awesome coming on. I haven't talked to you guys in years in person, just messengers. Yeah, exactly man. One of these days. Of course we were gonna trail off a little bit here and there's been a lot. Yeah, it was a great time, man.

Appreciate it. And with that, we'd love to thank you for joining us each and every week. You can find us on our social medias, at Facebook, Instagram, TikTok, and on Patreon, where you can get early access to these episodes by up to one week. Give us a rating review on your podcast platform of choice. It helps people find the show.

Bermat, for Brad, I'm Kyle and we will see you again here soon. See ya. Blamity blam. Ah! Brain soda.