Dynamic Dialogue with Danny Matranga - 385: 12 reasons to supplement with creatine
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Hey everybody, welcome into another episode of the Dynamic Dialogue Podcast.
As always, I'm your host, Danny Matranga, and in this episode, we are talking all things
creatine.
You see, when I was scouring a recent Q&A to determine what questions I'd like to pull
for a recent episode or upcoming episode,
this one will probably have dropped by the time you hear this, I just couldn't get over
how many questions there were about creatine.
And I said, you know, it's been a while since I've discussed the reasons and the rationale
behind creatine supplementation in long form, with some science with some evidence that
expands beyond just the enhancements
in musculature and muscle strength and in the stuff that's so frequently discussed when
we discuss creatine. So really deep diving here and unpacking creatine for a little bit
in a kind of dedicated episode that I think will bring many of you up to speed and serve
as a great resource moving forward. Enjoy.
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So when it comes to creatine
I think what I need to you know get across first is we're going to be talking about creatine
Monohydrate that is the form of creatine
I will be referencing because
all of the studies, all of the science, all of the evidence basis that I'm
referencing when I say creatine can do this, creatine may help with this, etc
etc. Those claims are backed by research showing the efficacy of creatine
monohydrate. Okay, there's other forms. This is the only form I would recommend,
creatine monohydrate. Another housekeeping kind of question before we
get into it, who can take creatine monohydrate? Pretty much anybody who
doesn't have a pre-existing maybe kidney or liver thing, you should always check
with your doctor. I'm not a doctor, but they have studied creatine safety in
women, men, teenagers of both genders, children, even
infants, breastfeeding women, and there are no, you know, standout red flags. Okay, still check
with your physician, but the safety profile of creatine is extremely high compared to other
supplements. Another question about creatine that's a good rules for the road thing. What
the hell is it? It is a combination of a few amino acids.
It's organic, we make it in our own bodies,
we tend to get it in our diets from red meat and fatty fish.
If you are active and do a lot of work
where you contract your muscles,
or you care about specifically the development of strength,
speed, power, athleticism,
creatine supplementation probably makes sense.
But there's a lot of other reasons to take it, which we'll probably outline today.
The safety profile, like I said, is very high.
So is the affordability.
Creatine is one of the most affordable supplements on a per serving basis.
Additionally, it's pretty widely available, easy to access in good forms.
And frankly, as far as supplements go, while some people do often, I'd say like 5 to 10%
of people communicate either headaches or GI distress, most people have zero side effects
associated with creatine supplementation whatsoever.
So let's get into why you would take it 12 reasons
really to supplement with it beginning with the first four which we're going to
categorize under the umbrella of physical performance. So the first and of
course most obvious reason you might want to take creatine is for increased
muscle mass actually building more muscle. Now, I will be honest with you,
the literature I've seen around just how much muscle
creatine can help you build is a little bit unimpressive.
It seems to me to be the case that creatine might make
a 10 to 25% difference in the total amount of muscle
you build as a natural athlete,
and man, I'd probably skew closer to like the 10% side,
and most of that's indirect. It makes
a difference but not a huge difference but we can say that creatine via either direct mechanisms
that grow the cytoplasm, the actual innards of the muscle cell, the the liquid part via mechanisms
that just allow for more mechanical tension to occur over time that you should see increased muscle mass with creatine
supplementation
One thing for sure we're gonna see moving on to the second reason to supplement with creatine is
Improved strength and power so a lot of you might wonder okay
How is it that I can you know actually develop more strength and more power?
Like, how does creatine literally help me do that?
It's not steroids.
Is it it actually is through ATP, which many of you probably have some
familiarity with and might remember from high school biology class.
ATP is one of those things that you learned about for sure.
It's made in many cases in the mitochondria,
the powerhouse of the cell.
And so long story short,
when you're doing vigorous exercise,
you deplete ATP pretty quickly.
And creatine helps regenerate ATP from ADP
by carrying a phosphate group back to ADP, turning it back into ATP.
So that's going to help with energy production inside of the cells.
And it's interesting, a lot of people tend not to remember this, but you have many different
mechanisms of ATP production or energy production, muscle contraction in the body. One of them is the ATP PC system, the adenosine triphosphate or phosphocreatine or
phosphagen system. That powers some of the most explosive exercise we do. I want
you to think of the hundred yard dash. That's actually powered in many ways
just by ATP and creatine. Not by carbohydrate, not by fat. Walking up a
gentle incline, that's gonna be mostly fat.
Doing 12 reps on the bench press,
that's gonna be a combination of creatine,
but mostly probably glycolytic.
However, it is through this phosphagenic pathway
that we produce a ton of power.
This is powered in large part due to stored creatine,
and having more stored creatine can help with this.
The third way creatine can enhance physical performance, the third reason to take it,
is for the enhanced recovery.
Creatine can reduce cell damage and inflammation following exercise, leading to better recovery,
and it can also help you hold more fluid in your muscle tissue, which is generally going
to be beneficial for
recovery. It could also be the case that creatine may help with the absorption of
other nutrients or when consumed with nutrients like protein and carbohydrate
might have enhanced absorptive qualities. So it's not a bad thing to take around
your workout or post-workout. It should get into your muscle cells pretty
quickly and pull some water in there with it to help with recovery and it to take around your workout or post-workout. It should get into your muscle cells pretty quickly
and pull some water in there with it to help with recovery.
And it might even bring some amino acids in with it.
The fourth reason to take it is for increased
long form output, you could call this endurance.
Now creatine is primarily going to be beneficial
for high intensity output, specifically the
sprinting work, the high power work, the high rep strength work we talked about, but it
could also be beneficial for endurance athletes.
So I wanted to highlight that as a fourth reason to take it.
It is not just beneficial to have for people who do a lot of power training.
I would say creatine is highly beneficial even for aerobic athletes
as it helps with that little bit of like, NOS or like extra gear that you need to tap
into sometimes. Having a little creatine on board could very well help with that.
Now, let's talk about another area where creatine supplementation has really garnered a lot of
attention. And this is the area that I'm probably the least qualified to talk about because
I am not a cognition expert. I'm not a brain expert. However,
I've recorded multiple podcasts with people in this field and creatine
experts,
where we discuss the link between creatine and the health of the brain and the
long-term capabilities and facult health of the brain and the long-term capabilities and faculties
of the brain.
And I continue to be impressed.
No matter who I talk to, I remain pretty impressed with how creatine can impact our brain.
Now it's important to remember in the body, most of the creatine we store is in our muscle
tissue for all the reasons we outlined earlier.
Increased muscle mass, improved strength and power,
enhanced recovery, increased endurance.
Wouldn't it make sense that if you supplemented
with creatine and got those benefits,
it was probably because a lot of that creatine
was going to your muscles?
Duh.
And that's what happens.
But not all of the creatine goes to your muscles.
In fact, some of it goes to your liver
and some of it goes to your muscles. In fact, some of it goes to your liver and some of it goes
to your brain. And it's interesting that it seems to be that there is an association,
this does not mean anything, but there is an association between creatine supplementation
and improved cognitive function, especially in short-term memory and quick thinking in older adults. And
to me that might make sense because I know this is true for a lot of my older
clients as they age, their dietary practices change, their appetite changes,
and oftentimes this reflects, I don't want to say a disinterest, but certainly
less excitement around the ingestion of large amounts of meat.
This is a trend, this is not general, so I can't say this is true for everybody,
but I've generally seen, or I'd see a trend of as people age, they tend to eat a little less meat.
It doesn't mean less protein, just less meat, and that could mean they get a little less creatine. And it could be the case that they don't get enough. And when
they eat just a little bit more red meat or supplement with creatine, that additional
creatine that can be partitioned to the brain can really increase their cognitive output.
And I say this because I have yet to see literature that's as encouraging for younger people in
terms of cognition.
We'll talk about mood in a second
and how interesting I think that is.
Creatine and mood,
there's some really interesting research
on creatine and depression.
But to me, just fascinating.
Creatine clearly accumulates in the brain.
It certainly seems to help a cohort of people
who might not eat as much red meat, cold water water fatty fish, or creatine rich foods or supplement with
creatine and when you give it to them, much like that is often the case in
literature where you give it to plant-based dieters, they see an even
greater benefit. So seniors, anyone who wants to, you know, improve their
cognition, short-term recall, I would definitely recommend this for healthy seniors,
anyone with Parkinson's disease,
anybody with a motor disease where muscle loss
or sarcopenia might be enhanced, an absolute must,
in my opinion.
That was the fifth reason to take creatine.
The second of two in the category of cognition
and brain health is neuroprotection.
So creatine has shown some potential
neuroprotective properties.
I was first introduced to this about five years ago
in Sacramento at a sports, what would we call that?
Sports performance, sports physiology symposium
where the Sacramento Kings play, that NBA team.
They have the Golden One Center,
that really beautiful arena,
and underneath they have a pretty bad,
pretty bad ass practice center and sports science facility.
And they had a woman from UC Davis there speaking
about creatine and fish oil and their efficacy
as neuroprotective agents in combat sports,
in contact sports where concussion is high.
And I thought it was fascinating because some of the follow-up literature and follow-up
commentary I've seen since has been so strong and so robust as to say that like if you let
your kid play football but you don't like let your kid take creatine, you're a bad parent.
Because there's so much emerging literature about like creatine and TBI, traumatic brain injury,
and a lot of parents are worried about creatine because they don't understand the safety profile
and maybe they've seen it misrepresent or had it misrepresented to them as being potentially
a steroid or a performance enhancer that might harm the health of their child.
So I understand that.
But wow, can creatine be uniquely helpful in that category? And there are some promising snippets of literature around certain neurodegenerative diseases.
Of course, my dad having Parkinson's when I saw there might be a connection between
creatine and Parkinson's, I got super amped.
But in general, it's very difficult for me to say that I see a particular...
It's hard for me to say that I see a particular path forward for anything more than creatine
helping these diseases in indirect ways.
Could it help the brain?
Indirectly, yes.
Could it help the muscle loss that's associated with certain neurodegenerative
diseases like maybe MS and Parkinson's? Yes. But I would never, I would never, ever want
to give someone too much hope. It tends to be the case that when you are using supplements
to enhance, to entreat illness, you end up improving quality of life. But, you know, treating illness is more
for doctors, not for podcast bros. But the literature to me is exciting. And I think that
anybody who's dealing with a neurodegenerative illness should totally talk to their doctor and
see what they think about creatine. Let's talk about general health and wellness as a category
that I have four things written down for. So the one of them, two of them, frankly, three of them you could argue are very similar
to what we just talked about with neurodegenerative disease.
But the first is just general healthy aging.
We already talked about how creatine can increase muscle mass, strength, power, and enhance
recovery, muscular hydration, and ability to just
perform work. That tends to become harder and harder as we age, and healthy aging
also coincides with sarcopenia, muscle loss, osteopenia, bone loss. We will talk
about one of those in greater detail, but in this example specifically, when I talk
about healthy aging, I talk about, I mean
aging with muscle, contractile tissue, so you can do shit and your quality of life remains
really good comparatively speaking, right? Like compared to the other people your age,
you're able to do the shit you still want to do. You've made less concessions in life.
Creatine supplementation can certainly help with that. I think all six of the points
we've made so far in improving muscle mass strength, power, recovery, endurance, cognitive
function and neuroprotection make this probably a must take for any healthy senior that can
clear it with their physician. But I would just say the seventh reason to take it, the
first in the category of health and wellness, is this is up there in my opinion in terms
of just
a generally good supplement to support overall healthy aging.
Now let's talk specifically about the population of osteopenia and osteoporosis, people with
diminishing bone density.
So one thing for sure that most physicians would prescribe to anyone with osteoporosis
and osteopenia is some type of weight-bearing exercise. How weight-bearing that might be
depends on specifically your physical capabilities and all of these things. But one of the common
things is swimming, weight training, walking, calisthenics, anything like that. And if you
pair those things with creatine, you actually see improved bone health. So, people with osteoporosis, osteopenia, might benefit uniquely from supplementing with creatine.
And that's a very common and very prevalent diagnosis.
And you see people take things frequently, like collagen, frequently like glucosamine and chondroitin,
that I'm not going to say don't have any evidence to support their use,
but they don't have nearly evidence to support their use,
but they don't have nearly as robust a use case as creatine, and they don't have as nearly
as many ancillary benefits.
The third is blood sugar regulation.
You could call this glucose metabolism.
You could call this blood sugar, and that would be creatine's unique in that it can
improve glucose metabolism.
This could be because oftentimes when we study people who take creatine, unique in that it can improve glucose metabolism. This could be
because oftentimes when we study people who take creatine, they're often active. But it
seems to be the case that creatine is associated with better nutrient partitioning, specifically
carbohydrate partitioning could be beneficial. If you are a little more sedentary, maybe having
a harder time managing your blood glucose. And again again with management of blood sugar more muscle tends to help contractile tissue acts as a glucose sink, a
reservoir if you will for muscle or for glucose and so the more muscle you have
the more insulin sensitive you often tend to be. Again this could be and this
is something that I actually learned quite a bit about from a client who I
worked with for a very long time. She was a teacher in Australia and one of the
things we talked about on the phone when I first onboarded her was her dad had a
muscular disease. And there are some muscular diseases where in which
creatine has actually been used as a therapeutic aid such as muscular
dystrophy. And that was one of the things we ended up talking about and I ended up
researching. She wanted to know if it was safe to take and it ended up being the case that in her specific
context it made a ton of sense and it even maybe ended up making sense for her dad who had this
muscular condition and it opened my eyes to the fact that hey there are certain populations who
would benefit from taking this even if we classically don't think of them as quote unquote fitness able. They might literally have a motor disability or a muscular
disability and you might think, well, what good is a supplement that helps with muscle
mass for someone like that? And you know, I would say it may could make a huge difference.
Um, you know, we have to look at outside of the realm of just sports
performance when we think about how these kinds of things
might help people and might make a difference.
And creatine is just one of those supplements
that I think, like fish oil or omega-3s, like vitamin D,
like calcium, multivitamins, is going to hopefully become so mainstream that people take it,
and I could be wrong, and if it ends up becoming the case that creatine was a bad idea, I'd
be shocked, but if that does end up becoming the case, I'll definitely change my position
to reflect whatever is safest for everyone, but it seems like creatine's so damn safe
for so many people that, you know, for healthy aging,
for people who have bone degeneration, muscle loss,
irregular blood glucose, neurodegenerative diseases,
have any desire to look or perform at a high level,
or even a muscular disease, creatine probably makes
sense.
So here's two additional benefits, number 11 and 12 that I think are kind of interesting.
So one thing you'll hear a lot when it comes to creatine is, ah, what about the water weight?
And so creatine actually does add water weight, but in a good way, and it improves hydration
in the process.
So creatine draws water into your muscle cells. That's where the water weight
goes. Not in your skin, not into fat, in your muscle cells making them look fuller
which is cool right? But creatine also helps maintain the right hydration status
which could be good for getting a pump, performing a little bit better, and
looking a little bit better in a tank top. The second thing that's cool that I alluded to earlier, and again, I have not nearly as
much evidence to support this as I do some of these other claims, but it's some of the unique
kind of exciting evidence on creatine's potential ability to alleviate certain symptoms of depression. As somebody who has been diagnosed with
depression, it's definitely cool to me to see that creatine could be helping me in
that area. I have not tried to, you know, take the time to directly correlate my
symptomology with creatine supplementation
because I take creatine every day
and some days I am depressed, some days I'm not.
I'd say for the most part I do a pretty darn good job.
And that is another reason I might tip my hat to creatine
because, and I've said on the podcast many times,
I'm not anti-medication,
but I'm able to manage that pretty well.
And one of the regular daily consistent things in my routine is creatine for what it's worth.
So 12 reasons to supplement with creatine that I believe are evidence-based and sensible.
You can, number one, expect for some increase in muscle mass compared
to taking nothing. Number two, certainly expect increases in speed, strength, power. Number
three, expect a little less soreness, better hydration from hard exercise. Number four,
expect a little bit more juice even for endurance athletes. Number five, better cognitive function
for seniors and aging adults. Jury's still out for young people.
Number six, could be neuroprotective long-term.
Number seven, right up there with some of the best generally healthy aging
supplements I can think of.
Number eight, improve bone health and bone density.
Number nine, better glucose regulation, blood sugar management.
Number 10, could be beneficial for diseases that affect the muscle system.
Number 11, definitely going to help with hydration.
And number 12 could be interesting for people dealing with depression if you can clear it
with your doctor.
Again, I'm not a physician, guys.
These are just general, my general consensus on the literature.
I'm very bullish on creatine. I think it's a great supplement.
I take Legion's creatine monohydrate, it's a very affordable form.
One bottle could last two months if you're on the smaller side and take a 3 gram a day dose. I take almost 10 grams a day, no issues.
Anyway folks, hope you have a wonderful day, thanks so much for listening, leave me a 5
star rating and review on Apple Podcasts or Spotify, and I'll catch you on the next one.