Joe Rogan Experience Review podcast - A Review of 1234 David Sinclair

Episode Date: February 2, 2019

A Harvard Genetics professor and longevity researcher. David had a lot to say about living a longer healthier life. Check out his conversation with Rogan and takes some notes as there’s a lot to dig...est. Definitely worth listening to. Enjoy my review folks! Please email me with any suggestions and questions for future Reviews: Joeroganexperiencereview@gmail.com

Transcript
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Starting point is 00:00:00 Hello and welcome to another episode of the JRE Review. Today I'm reviewing podcast 1234 with with Dr. David Sinclair. This is a fascinating conversation and somebody that I think Joe has wanted to get on for some time. It seems like the theme of the week is having anti-aging professionals on and people that know everything about health and longevity and this and that. I mean Later on in the week he has Ben Greenfield on and Ben Greenfield's like a wealth of knowledge as well But this conversation when you're listening to Joe's podcast on this, you know Don't be afraid to take some notes if you're into to Joe's podcast on this, you know, don't
Starting point is 00:00:45 be afraid to take some notes if you're into finding out what the best supplements are for taking care of your body and living a long time. That's what I would say, but otherwise it was fascinating, so I'm going to start the review. Welcome to the Joe Rogan Experience Room View! Where each week I review every single episode of the Joe Rogan Experience. One more do you want? As I said, Dr. David Sinclair is a genetics professor.
Starting point is 00:01:20 So he's a professor at Harvard and deals most of his focuses on Anti-aging longevity studies that sort of thing so he does a lot of testing on mice giving them different compounds and seeing how he can get them to live longer and also some other Creatures, I think like more singular cell type things. So I guess that's how the science is done. And there we go. He then uses that information and kind of applies it to himself in a way before human trials have started. Now it sounds a little bit sketchy
Starting point is 00:01:58 when you're doing experiments on yourself, but I mean all he's taking is just compounds that are either already given to humans in some amount or have been, you know, they used this like prescription jug or something else, so it's not like he's just trying any wacky new things that nobody's ever tried before. Then he uses some company called Inside Tracker, I think it's like a blood testing company, and they give you a lot of metrics and results on your blood. They kind of let you know where your level stands. Now, I have a feeling that when they send that back to you, it's
Starting point is 00:02:39 probably doesn't even mean a lot to the regular person, but since he is a doctor of genetics and understands kind of these lab results, maybe he can make sense of it. Maybe not, maybe it is pretty simple, maybe it's like you need more carrots. I don't know, I don't know. David was originally from Australia, so he has a bit of an accent on this podcast and it's not super Australian though, he's obviously been in the US a long time and before he started working at Harvard he went to MIT so all around a brilliant guy, always thinking hard and working hard, he's also owned many companies that have done well, all kind of in the lines of anti-aging type companies. He doesn't really specify, but the idea was all things
Starting point is 00:03:34 designed to kind of help humanity and anti-aging. So it's not about mega profits and and boosting you know stock value and all the rest of it. Though he has made some money, he did a loot to selling some company, he was a partial shareholder in for, I think it's all for like 700 million something ridiculous. Anyway, so he's got some money and he can use that money now to put it into these new company ideas and I think his focus is just really is the kind of help humanity and get his work done and learn some things. So he gets into different ways of
Starting point is 00:04:15 increasing life span, intimate and fast thing is a good one. That seems to work in a lot of different creatures and mammalians that they've checked on and they're starting to think that it definitely shows good effects and people. I don't know if you've ever tried intermittent fasting it's basically where you like don't eat for 16 hours and then you only eat in like a window of eight. You can do it in like 10 and different amounts and you can do it for a few days and and then eat regular different things like that but it it seems to work for people I've tried some form of it and
Starting point is 00:04:49 It's it's certainly easier than you would think and you feel pretty good, you know, so so at least that I know but But yeah, it's it's something that try it see if you like it but yeah, it's something that, try it, see if you like it. But he's saying it's good. And he's saying you should be hungry for a period of the day as well, which is kind of an interesting thing to think because people don't often like being very hungry. Joe asked him obviously a lot of conspiracy theory things,
Starting point is 00:05:20 like what are people trying? A scientist using CRISPR to genetically alter humans and are there clones and those sorts of things like you know Joe loves to get into into the conspiracy side of stuff or at least ask the questions and and what was interesting is David actually works for government agencies that kind of oversee the actions of different countries and what they're up to. One thing he knows for sure is some doctor in Japan used CRISPR to remove some of this gene that allows people to get AIDS from their body. So these two
Starting point is 00:05:59 kids could never get HIV. And the doctor just did this, and then released the findings, and it was seen as kind of like taboo, like not really a good thing to do, to just kind of throw out there, because since he didn't really keep all the research transparent in that sense, it's like, well, maybe if it had gone horribly wrong, he wouldn't have announced it at all,
Starting point is 00:06:24 and it's just one of those things. So, so, David's kind of annoyed about that and a lot of scientists are because they're also worried that it might put the spotlight back on that sort of research, and they don't want what happened during the Bush administration with stem cells where there was this big push against the research because they thought I don't know that it was like playing God or something like that. So they definitely want to keep that open and find out more about what Chris could do. So scientists, you know, he's saying they need to be more careful about kind of how they're releasing that information, that sort of thing. My question was like, what did the parents ask for this? Or did he just say, hey, I'll just do this to your kids if you want?
Starting point is 00:07:12 It just seems like a strange thing. I don't know why anyone would allow that to happen. And HIV is not very, or AIDS is not very common place in Japan. So from what they were saying. So I don't know. It just sounded strange to the anyone that even bother. Like imagine how messed up your kids could be and you're like, well, they weren't even going to get this anyway. Well, he towards the end of the conversation, Joe is asking a lot of questions about what he takes in particular, what David's and Clare takes, being that he is an anti-aging specialist.
Starting point is 00:07:46 And that's a good thing to know, right? It's like, what are the chefs eat at the restaurant they cook at? That's a good question. It's because they're always gonna eat the best thing. And in the same way, what are these guys taking? So it's one thing to just say, what does what? And different types of lifestyles are helping
Starting point is 00:08:05 But Joe really got into it about how he works out does he use saunas does use saunas He believes in that and he believes in the research about longevity from sauney use Also something called rust veritrol which is from red wine and That's supposed to be a very good Anti-aging supplement actually bought some because Amazon had some real cheap And I'm like what the hell tried out if this guy says he's good I mean really how smart you need to be to be a genetics professor at Harvard that came from MIT It's going to know what he's talking about. He's not just throwing it out there and he's on his Products anyway, it's not like he's selling them. There was another one called N-M-N,
Starting point is 00:08:47 which I looked up online and it's incredibly expensive, so I won't be getting that. But that one also plays a role with Rosfaritrol in promoting anti-aging. He basically said Rosfaritrol was like the accelerator and N-M-N is like the fuel. And if that is the case, my dumbbell brain is saying that maybe without NMN Russ Faratroll is not even gonna work, but Oh wow, fuck it was only like
Starting point is 00:09:16 $12 or so, it doesn't matter, I've tried out. But yeah, NMN is very expensive, won't be getting on that one. There's another one called Met Forman, which he said is actually medication for diabetes, which David does not have, and he stresses that multiple times on the podcast, but research has shown people that take Met Forman actually have reduced risk of a lot of different times of illness, heart disease, cancer, some other ones, I'm not exactly sure, we're all of them, but yeah, so there's that, which I found pretty interesting, like he doesn't even have diabetes and he thinks that this medication is a good one to get on, so, you know, again, I mean he's an expert, he must know this, I'm not saying everyone should get on it, but it makes
Starting point is 00:10:01 you think, but it reduces all kinds of illness illnesses and it has a pretty drastic effect. So those are the three main ones. It doesn't take a lot of other supplements. I don't think it drinks a lot and you know it does get some exercise in. But it's a fascinating conversation. It's one that if you're into living a long time being healthy and not having Alzheimer's and other diseases, which really you should be, because come on, I mean, it's going to get you eventually and you're going to wish you had taken care of yourself by the time you get there. Listen to it, take a listen, you know, and with the Ben Greenfield one coming up, which I'll review shortly, I'm sure, these podcasts are really good ones to take some notes
Starting point is 00:10:50 and see, you know, if there's any minor changes you can put in your life, you know, I really think in a lot of ways, this is not just for people that are trying to be super healthy and live a long time, but maybe you're pretty sedentary and you don't work out a lot, and you just don't have the energy, and you're like, well, shit, is there anything I can do that's fairly simple, like take a few pills that might help lower blood pressure and other things, and this is where these types of podcasts come in, and this is where they get, you know, where you can get a lot of good information from. But anyway, I really enjoyed the podcast, it's an interesting dude, super smart,. But anyway, I really enjoyed the podcast. It's an interesting to super smart.
Starting point is 00:11:27 Check it out and thanks for listening guys. you

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