Mind Pump: Raw Fitness Truth - 2332: How to Slow Down Aging With Dr. Stephen Cabral
Episode Date: May 9, 2024What is the difference between your biological vs. chronological age? (2:10) What metrics does the test cover? (3:17) Have they connected these markers/tests to age-related symptoms? (5:03) Th...e success of reducing one’s biological age. (7:07) Why all these specialty bio hacks are worthless if you’re not healthy. (9:07) Good vs. bad methylators. (10:26) It all comes down to bio-individuality. (16:33) Revealing the guy’s Biological Age test results. (18:31) Adam. (22:01) Sal. (25:22) Doug. (26:30) Justin. (29:00) Who is more neanderthal? (30:11) What causes us to age slower or faster? (33:04) The top supplements to slow aging. (33:52) How anything that is good for us can be negative if taken too much. (39:39) The best methods to reduce oxidative stress. (44:05) It’s all about finding the right level for you. (51:15) How often should one take this test and where can you get it? (53:56) Related Links/Products Mentioned Discover Your True Biological Age & Reverse Aging with This Cutting-Edge At-Home Lab Test Visit Eight Sleep for an exclusive offer for Mind Pump Listeners! ** Get $200 off plus free shipping on the Pod Cover by Eight Sleep. Stay cool this summer with Eight Sleep, now shipping within the USA, Canada, the UK, select countries in the EU, and Australia! ** May Promotion: MAPS Strong | MAPS Powerlift 50% off! ** Code MAY50 at checkout ** What Is the MTHFR Gene? - Healthline What Is a Whole Body MRI Screening and Why Should You Get One? Mind Pump #2272: The Dangers Of Heavy Metals & How To Flush From Your Body With Dr. Stephen Cabral Homepage - High Performance Health Visit Joovv for an exclusive offer for Mind Pump listeners! ** Code MINDPUMP to get $50 off your first purchase. ** What's Worse: Marijuana vs Alcohol | Cabral Concept 2735 Adrenal Soothe-Equi.life Cabral Concept 2938 - WW: The Simplest Way to Reduce Stress & Cortisol Mind Pump Podcast – YouTube Mind Pump Free Resources Featured Guest/People Mentioned Dr. Stephen Cabral (@stephencabral) Instagram Mark Hyman, M.D. (@drmarkhyman) Instagram David Sinclair (@davidsinclairphd) Instagram
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If you want to pump your body and expand your mind, there's only one place to go.
Mind pump with your hosts, Sal DeStefano, Adam Schaefer, and Justin Andrews.
You just found the most downloaded fitness, health, and entertainment podcast.
This is Mind Pump.
All right.
Today's episode, we have our good friend, Dr. Steven Cabral, one of the best functional
medicine practitioners in the world.
And today he gives us the results of our biological age test.
So this is a test that looks at many different factors that will determine what your biological age is.
And yes, it can be different than your chronological age.
So you can, in this episode, figure out if I'm older or younger than my actual age.
Same thing with Adam, Justin, and Doug.
And Dr. Cabral
talks all about the markers that they look at and how to make yourself younger than your
years. It's pretty cool. Anyway, you can get yourself one of these tests at stevencabral.com
forward slash bio age. Steven is spelled S-T-E-P-H-E-N. Now this episode is brought to you by one
of our sponsors, 8 Sleep. They make a device that goes over your bed,
it uses water to cool or warm your bed, and it also uses AI technology to check out your REM stages of sleep and
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go to mapsfitnessproducts.com and then use the code May50 for the discount.
Alright here comes the show. Dr. Cabral welcome back. Now this is going to be an
exciting episode because we tested our biological age, right?
What's the name of the test? There's a full name to it. It's like health span and biological age.
Yes, biological age test. So there's multiple companies that run this right now, but there's
only four that are legitimate and we can talk about that. But I think this is going to be a
really fun show. Probably one of the most fun we've had because there are actually winners to this
lab. Like who is aging the slowest? That's what we're going to look at.
We'll see how fun this is going to be.
What's the, okay, so what is the difference between biological age and your chronological
age? Like you're, you know, you're, you're, you're 30 years old because you were born
30 years ago and then your biological age shows something different. What does it show?
Yes. So you have a chronological age, which is like you just said, literally the number
of birthdays that you've celebrated that you've been on this earth.
And so it's also, that's why this is not the best thing for your doctor to say,
oh, these diseases, literally just a disease of old age.
Okay.
Well, maybe not because your chronological age, you can be, let's say 45 years old,
but your biological age is what your body looks like for the average 30 year old or
45 year old or 55 year old.
So your biological age can be three different
things, the same as your chronological age,
lower than your biological age, which is what we
want to strive for or higher than your
chronological age.
Now, if it's lower, the biggest benefit is that
you are literally aging slower.
So let's say that,'s say that the average individual,
they live 74 to 77 years old in the United States, your goal would have a lower and slower rate of
aging so that you would then naturally live longer.
Okay. What are they testing to figure this out? What are the metrics and how do they figure these
out? They're testing hundreds to hundreds of thousands methylation points on your DNA.
So that's why when you run this lab, you are doing
either a cheek swab typically, or you're doing a
blood collection.
Okay.
And then either one of those, they can take actually
the white blood cells and they can look at the
markers on that.
And how did they figure out that these markers
indicate faster or slower aging?
How did they figure the correlate or the connection?
And it hasn't been easy for them because I've been
using these tests now for 15 years and it was so
rudimentary 15 years ago. Remember Taylor-Meyer testing?
Yeah.
Yeah. I was going to ask you about Taylor-Meyer.
Wildly inaccurate, like six to nine years, plus or minus.
Wow.
So imagine testing your body fat and they're like,
yeah, it's six to nine plus or minus. So like, okay, so I'm either 12% or 20%.
Or 6%.
Exactly.
Something seems off here.
So they've just continued to refine it over the years.
And so two things I'll say is one, there's no golden,
they call it the golden index yet.
And that means like, this is the ultimate standard
for how this test should be run. They're all running them kind of the same, but they're just golden index yet. And that means like, this is the ultimate
standard for how this test should be run.
They're all running them kind of the same,
but there's no golden standard.
Now, the nice thing is that it's no longer six
to nine years plus or minus, it's around six
to nine months.
And so even though it's not perfect, you're
getting it like, if you're 45 years old and it
says you're 44 or while you're doing better, or it could be 46. So it's like, it's not that much because you can get a, say if you're
45, it can show that you're 54 or it could show that you're 35. So you know that you're on the
right, moving in the right direction and they believe in the next three to five years we'll
have such good accuracy. It will be within 60 to 90 days maximum. Now have they connected these markers in these tests to age related symptoms,
like fatigue, insulin resistance, bone, I mean, muscle loss, bone loss,
like all the things that we can connect to aging.
Have they been able to connect these metrics to those types of symptoms?
They've been able to connect the specific DNA sites that we're going to talk about here today
with cardiovascular risk, with type two diabetes, with blood pressure, and with Alzheimer's, so dementia.
Wow.
And they actually give you a rating as to how likely you are to die from one of those or get
one of those. And that's called the epimetabolic index. So it's a really, you want to be below a
6.3 and the lower the better. So you have less chance, less risk for metabolic syndrome.
Metabolic syndrome is basically high cholesterol, high triglycerides, blood pressure, diabetes,
like everything's off, all the markers.
And the only thing that this test is not good at looking at is cancer.
So it's not going to give, you can be a totally healthy individual with a lower biological age,
and still this doesn't look for cancer. So it's important. I just want to point that out because I like to be unbiased with this age and still, this doesn't look for cancer. So it's important.
I just want to point that out because I like to be unbiased with this and just
say, this isn't testing for that.
Okay. So you might not know the answer to this,
but I do know that they do testing with biological organisms where they'll have,
they'll put one out in a satellite and then they'll leave one here and they'll
compare the aging because the faster something moves, you know, through physics,
the slower it ages. Have they made,
is this what they use to measure
whether or not something's aging slower or faster?
Do you even know that?
I don't know if that's what they use for that measurement,
but highly likely, because this is the best way
that we have to measure.
But you're right, they're actually looking at that for,
and I'll sometimes read articles and they're like,
oh, okay, this is how we're going to get to Mars.
This is how we're going to be able to do longer travel is that the entity,
the biological entity is going to age slower, but
is there also a way that we can maybe freeze the
individual, keeping them alive, and then when they
arrive at whatever destination, we warm them back
up literally and bring them back to life. So I think
that that's fascinating. Mainly I'm on the testing
end of it and I would
love to see what that looks like.
How successful have you guys been through
your protocols at changing people's biological?
And how often would you test?
Like example, you know, like let's say your
biological age is five years older than your
chronological age.
How long would you need to wait with protocols
to test again, to see if you've made an impact?
So I test myself every three to four months.
We test clients that aren't practiced every six months, four to six months maximum.
And the reason is if we're looking at, again,
not a perfect science, very good science.
Let's give it like a B plus.
It's not in the A range yet.
We want to give the body enough time to adapt,
which is typically
three to four months to see change, and then we'll rerun that lab again, four to six months,
and then we'll be able to see the change. We've been very successful at reducing biological
age and obviously I keep myself to HIPAA compliance and all that, but I will tell you when I first
started running these labs, I had just opened my second practice in Boston. I had my, my child was a newborn at
the time. I was getting very little sleep. I was
not exercising as much as I should, tons of stress,
very little sleep. My rate of aging was well over
a one, which means I was raging, aging faster than
my chronological age. And my, I was in my thirties
at the time and my biological age was in my
early fifties.
It was horrible.
And I said, okay, uh, this is bad.
So I already have a history of like health
issues when I was much younger.
And so I said, we need to do something now.
So that's actually when I started this
research about 12 years ago.
And I said, I'm just going to study it and start
to use it and then begin to implement it.
And the fascinating thing is that the
lifestyle changes have not changed at all, but the specialty things that we'll talk about here today
are what is changing and will most likely, you'll be able to, our age right now, we will be able to
reduce biological age by 20 to 30%, meaning I should say extend lifespan
by 20 to 30% in our lifetime.
Wow. Wow.
Now have you been able to connect symptoms
with the people you work with
and their biological age reversing?
In other words, they'll test six months later
and they're like, man, I feel way better
or I feel worse.
It's a great question.
So in our practice, we focus on,
so my background is actually,
as I started as an ACE certified personal trainer at 18 years old, then I got NASM certified,
then I got NSCA, CSCS certified and kind of worked my way up. And what I realized back in the day
doing nutrition and personal training is that people's health issues went away if I got them
in really great shape and gave them a good nutrition. Yeah. I didn't know why, but it's because it's the
cornerstone, right?
And so in our practice, we literally help people
to transform their body to a healthy body
weight for them.
And if there's any wellness based issues, we then
fix those wellness issues.
And then after that, we then work on anti-aging
because it actually doesn't make sense to do all
these specialty biohacks if you're not healthy.
Because what we've seen is people with autoimmune issues and inflammatory based disorders,
their biological age is quite high. And so they're like, should I start taking NMN or NR?
Or I'm like, no, we need to work on your gut health and your heavy metals and all these things.
Because you don't need the icing on the cake. We literally need to bake the cake first. We
need to create it before we can ice this.
And so that's what we do.
You mentioned methylation.
Can you explain what the, I hear a lot about that,
how people are good methylators and bad
methylators and I have to take this type of folate
or that type of folate because of whatever.
What is that and why are they looking at that?
So it goes back to specific gene and what are
called SNPs, single nucleotide polymorphisms.
So basically there is a amazing study.
So most functional medicine doctors believe
that maybe 5% to 10% of all disease is genetic,
meaning like innate genetic predisposition to
something like not high cholesterol.
I'm talking about cholesterol at 500 or 600,
like off the charts, right?
So that's, that can be genetically based.
But beyond that, we're looking at what are
called single nucleotide polymorphisms that then
turn on or off these genes and that's called
epigenetics.
So one of those is the methylene tetrahydrofolate
reductase gene, MTHFR.
So that's what we refer to it as.
MTHFR is, it seems super confusing.
The best way that I've ever found to try to be able
to explain it and even learn it myself is that on your DNA,
there are sites, specific sites.
And if you think about a 400 page book,
let's say you've read the book,
you don't memorize all the 400 pages,
but you actually marked the pages,
you dog-eared them or put bookmarks in.
The MTHFR, the methylation sites are telling the
DNA what to read, how to read it, and replicate
appropriately for that next time the cells turn over.
Does that make sense?
It does.
And so knowing that you can adjust certain
supplementation or whatever to help work with or
whatever.
And also what you're more prone to. So we know if you have MTHFR, so we'll talk about that. So
you can be, and you can have what's called 25% to 100% enzymatic activity of those methyl-based
sites. That means some people, they have no, there's something called homozygous and heterozygous. Right? So if you're heterozygous, both your parents give you copies of the MTHFR specific gene.
And heterozygous means one parent gave you, we'll call it a clean copy,
and one had some type of a mutation where you're not able to absorb folate as well.
And then if you're homozygous, that means both parents gave you specific MTHFR
based issues where you're only able to either convert 25% to maybe 70% of folate. And so that
is why we say to people, we love whole food nutrition. There's no doubt about that. We don't
like synthetic benign folate, which is folic acid, but even from nature,
you're not able to absorb folate and
convert it to methylfolate as well.
So there's a form of folate called five
methyl, methyl tetrahydrofolate, which
is very easily absorbed.
It's what we absolutely recommend for
every woman that's pregnant because she's
given folic acid, but she doesn't even know
if she can use folic acid, right?
For neural tube base dysfunction, et cetera. So we're big folic acid, but she doesn't even know if she can use folic acid, right? That's right. For neural tube base dysfunction, et cetera.
So we're big advocates of that, but folate also,
this is the misnomer that you only need folate
and you're good.
No, it's actually trimethylglycine or betaine,
it's called, vitamin B12 as methylcobalamin and B6,
which is typically paradoxyl 5-phosphate, P5P,
and then zinc, calcium, magnesium.
So it doesn't live in a silo,
folate uses all of those to be able to methylate properly.
Okay, so what's interesting about this is,
because this is obviously exists, it's a gene, right?
And people are gonna have it or they don't.
And we keep learning about how certain,
I don't know, learning differences or certain,
like for example, sickle cell anemia
and it now connected to being resistant to malaria.
So maybe it was a mutation to help people become resistant to malaria.
Are there any evolutionary benefits to having this gene?
Do they know why this exists?
Because it all sounds bad, but if we have it, I wonder if there's a reason why we have
it.
I don't know what the origins to that are.
That is very fascinating.
I know the origins of something we're going to talk about today, which is the apE genotype, the allele, because I don't want to get ahead of ourselves,
but the APOE genotype allele actually comes, dates all the way back to Neanderthal-based times.
And it's very rare to have it, but some people do.
So that to me is fascinating. I don't know how MTHFR actually came around.
Now, before we came on the show, I'll just share this now.
You did mention that this test does test those two things,
the APO, what is it called?
APOE genotype.
And the MTF.
MTHFR.
HR.
And you said, hey, you might not want to put these on air
because insurance companies may hear this
and can alter your premiums
because you have a higher rate of,
let's say Alzheimer's or whatever.
So, but this test does test those.
It does.
Okay. It will tell you if you're more prone to cardiovascular issues. because you have a higher rate of, let's say, Alzheimer's or whatever. So, but this test does test those.
It does.
It will tell you if you're more prone
to cardiovascular issues, how you metabolize fats.
So meaning like, we always talk about that cholesterol,
there's no big deal, there's no issue,
or some people demonize cholesterol
and say it's the worst thing in the world.
Well, there's a specific genotype, the APOE genotype,
and there are three, four, or four, four specifically. And they don't process cholesterol as well,
especially dietary cholesterol, even though it only
makes up a small amount of total cholesterol.
So they actually would do better, they found,
on a little lower cholesterol saturated fat diet.
Now that makes up 26% of the population.
So 74% are typically okay with it,
but that 26% sometimes gets lost
and they get swept under the rug.
So it matters for them.
And then also if you have the 3-4 or 4-4, specifically the 4-4, which makes up about
4% to maybe 6% of the population, they're 93% more prone to getting Alzheimer's. Does that mean
they're going to get Alzheimer's? No. It just means that they're more likely, they're more prone. Even
if you're an APOE genotype 2-2, even though it's protective, you could still get Alzheimer's.
You're just far less likely.
Now I heard or I read that creatine,
the supplement creatine is good for people
who have methylation issues because it's either
a methyl donor or allows your body to use
to methylate better because it doesn't have
to borrow from other places.
Are you familiar with this?
No, I'd love to be able to see that research.
Oh, interesting. I haven't seen it. Okay, cool'd love to be able to see that research. Oh, interesting.
Okay, cool.
We had someone on to talk about that.
All right, cool.
So let's see, I'm interested to see how old we are,
according to these tests,
and I might give you some pushback.
So you mentioned you were 50 the first time you did it.
How much have you been able to do in two years?
So this has happened over the last,
so three years ago to four years ago,
I really got into this
because the testing was much more, it was validated then. So now we're okay, we have legitimate tests,
we're able to do things that we know work. And so over the last three to four years,
so we'll put it this way, 15 years ago, my rate of aging was a 1.16. My biological age,
I believe was a 54. And at that time I was in my early thirties. I'm
about to turn 46 now. My biological age now is 32 years old. Wow. Wow. And my rate of aging is
between a 0.67 and 0.69 and 0.71. So those are my last three labs. Wow. So that is-
Gives me hope.
Gives me hope.
Yes. Yeah. And I was a, I mean, I was, I was a
disaster back then, even though I was healthy.
Like I was healthy legitimately, but I was
burnt out. Like my body was inflamed.
Sleep and stress, biggest factor for that?
Biggest factor. Sleep, stress, and yeah,
chronic based disease, which is inflammatory.
Wow.
Yeah, 100%. So there is hope, if there's hope
for me and my genetics, because I have a lot of
these issues that we're talking about, I won't
say specifically, but yes,
the MTHFR issues, the other issues, I have those.
So I'm far more prone to inflammation, but it
does show that if you dial these things in and
when I, we'll talk about the things that work as
well.
And so what I want to share is that for you,
it's actually, this all comes down to
bio-individuality.
What works for me is going to work for you, but
maybe not at the same level.
Got it.
You may be able to work out harder than me
because your body allows for that more than
mine might, right?
Or some people, they can run five or six
miles or half marathon.
The body holds up really well.
Like I know some people that are just great
runners, their parents were great runners,
they're great runners, where other people,
they get so inflamed, they feel terrible.
So everybody needs these things as just a varying levels and you have to find the right level for
you. That's why the testing is very helpful. All right. All right. So let's dive right into it.
We talked about already, we're going to go, we explain what the MTHFR is,
we explain what the APOE genotype is. There's basically six combinations. We won't read yours,
but I'm happy to answer more questions. What we are going to go over is the biological
age that we spoke about.
Biological age could be the same as your
chronological age, could be higher, which
means you're aging faster, could be lower.
Then we're going to go over what is called
the male index or the sex index.
It looks at how did you rank compared
to all men who took this test?
Oh God, you're going to hit us right in the ego.
And they typically separate it out.
Yeah.
And the reason-
And what are they ranking, Dr. Carolla?
Actually, I'm glad that they, actually, it's good that you
jog my memory in that too, because here's the thing.
They're not ranking all of the United States.
They're actually ranking pretty healthy people.
People who take the test.
Yeah, exactly.
So it's a little skewed.
It's not against you and the entire world.
It's you and your peers, people who are in-
That makes you feel a little bit better.
Yeah.
It's true.
You know-
Okay.
Just a little bit.
Not a lot, yeah.
Just to comment on the higher rates of things
like Alzheimer's stuff, you know, that's also in
the context of what they found for people who
live a modern life, right?
So maybe with this gene variance, your rate of
Alzheimer's 93% higher, but they're testing people
of this gene variance who also live in a modern
life and maybe live modern lifestyles. So in other words, there's a lot of hope. Yeah, without a doubt. of Alzheimer's 93% higher, but they're testing people of this gene variance who also live in a modern life
and maybe live modern lifestyles.
So in other words, there's a lot of hope.
Yeah, without a doubt.
And that's why, again, if I work with plenty of
people in my practice that are really three,
four or specifically a four, four, and we just say,
here's the, so I want to put people's mind at ease.
The technology and advancements in testing right
now will let you know if you're going to get
Alzheimer's 10, 20, 30 years ahead of time.
So one I would be remiss if I didn't mention it.
And that is a full body MRI.
And it's a non-contrast, so you're not getting
the radioactive dipole in your body.
We just talked about this.
And it's, so I have these 10 tests, they're
called the 10 vitality tests or 10 mortality
tests if you want to look at it from a
negative perspective. But if you run them on an
annual basis, you will not be, like there will be no
heart attacks at random, elevated blood pressure.
We'll see it way before.
Yeah, or cancer, anything. It literally looks at
cancer the size of a grain of rice. It's going to
look at Alzheimer's in the brain before, when it's just
developing.
And so the nice thing is nobody has to fear
Alzheimer's.
We can run this brain scan.
If your brain is clear, then you can wait a couple
of years and run it again if you'd like.
So anyway, full body MRI, I can't recommend it
enough.
Is it inexpensive?
No, it's not.
But these are things that I think are worth
investing in.
I think we found one up here in the area. It's like 2,500 bucks or 3,000. It's not bad for
something like this. Yes. 2,000 to 2,500 is typically the going rate and get them for a
little bit less when they're doing specials. And that's for the full body. And then if there's
no issues with the brain, you can go back and just do a torso scan once a year. And that's
$1,000 or $1,200. We've got to do this. And that will look for cancer. I definitely recommend it.
Yeah. I actually just ran mine about a year ago.
Okay.
So we'll look at the biological age, the
rate of aging, the DNA index.
That's it.
Okay.
We'll get started.
So I'm going to rank order you because I want to
have a little fun with this here today.
So we're going to go with the fastest rate of
aging,
highest biological age relative to their current age,
and then we'll go to whoever the winner is here specifically.
And-
I'm the big loser on that one.
Oh, this didn't, I have to now do the math in my head now.
Okay.
I'm pretty sure it's me.
All right.
It is Adam. Yes.
So you are correct.
Do you mind if I give, do you guys mind if I give you
Tell them everything.
Chronological age.
Let them all know how shitty I am.
It's not fix it.
It's like I said,
I'm missing cheese here.
I want you to know that like I picked up a pack of cigarettes in for Doug and I,
after we got these tests.
Screw it. We're done.
Yeah, it's all over.
That is just to calm your stress levels.
All right. Yeah, it's all over. That and just to calm your stress levels. Yeah, yeah. Yeah.
All right, well, chronological age is 42
and biological age is 49.
So, then we get that plus seven right there.
Woo.
Now what's weird about that is he's not any wiser
than a typical person.
That's not a core way of thing.
It can actually work in reverse.
Yeah, so I'm full of shit.
Sorry.
It's like no positives in there.
You're no positive in there, old man. Get your no positives. Get your shots in now. Yeah.
But this, so we'll look at the bright side.
This will really be amazing though, because you'll be able to see it go down if you follow
these specific principles.
Well, yeah, no, listen to me.
I mean, I'm excited now because of what you turned it around.
If you can turn it around from 50 down to 30 something, I feel confident I should be
able to at least get below my age chrono-alcohol.
Or we're going to start advertising.
Our sense of humor is young as hell.
Like one or the other.
Otherwise, you're going to screw this business.
Nobody's going to listen to us about health and fitness.
If yours continues to go up and up, we've got a problem here.
But it also shows though, this is important because you guys are all healthy.
You're all in great shape.
And so what we're looking at is internally, not externally.
That's why this is so important. So, um, okay.
Inside.
Not too good.
What is it?
Why on the inside is what counts.
So your youth scored better than 10% of other males that ran this specific lab.
Terrible.
And your rate of aging is 1.16, which means for every one year, you're
aging 0.16 faster than that one year.
You're faster.
I'm losing two, losing two months a year almost.
That's right.
That's, that is actually the best way to look at it.
So, um, when you're, when you're aging slower,
you're basically taking off a couple of years.
Yeah.
You're gaining, you're gaining a month every year.
Whenever I'm losing two months a year.
I'm losing two months.
You gotta get back on track.
Um, and then you're, I'm woke over your
epimetabolic index,
but it was excellent.
So like overall, like health-wise, genetics
as to predisposed, all of those look really good.
So that's interesting.
So that can look all really good,
but then I could still have this high biological age.
Yes.
Yep, absolutely.
Continue explaining, please.
And here's why.
They're looking at about seven specific genes
for your epimetabolic index in
terms of cardiovascular, blood pressure, obesity, et cetera. But that is not all the totality of
your current methylation sites. So one is specific genes that aren't ever going to change. And then
the others are epigenetic sites as to what's going on in your body right now.
So is that, I mean, I'm trying to get out of this negative mindset because I feel like that's not
even a positive thing for me either. It's almost sounds like I have all the good
genes I need to be healthy and young and yet I'm still not.
But it's in your control.
Right.
But you have the power.
Yes. And so here's off the air too, I'll share your APOE genotypes and those types of things.
And we can go through that as well for sure.
Now, does this make people moody if they're...
Stupid, dude.
Only if they're stupid? Huh?
Only after they read the results.
Yeah.
Yeah.
I've been in a bad mood for the last 24 hours.
That's for sure.
Not as great.
Yes.
Slow down.
The positive thing is you'll be able to drive down
these numbers and improve them.
Yeah.
Give me the secrets.
Let's go.
All right.
All right.
So those were Adam's results.
Next up is?
No, Doug.
It's Sal.
Oh, Sal.
Sal is up next.
Oh, Doug, you did that.
I do want to preface this by saying
I have the most kids here.
Oh, Jesus.
You're the only one.
Here come the excuses.
I'm doing pretty good.
Okay, hang on a minute.
Does this make him more Neanderthal or less?
Yeah, yeah.
I can actually give you the results
of who's the most Neanderthal.
I can do that. I want to know that one. That's gotta be you, Justin of who's the most Neanderthal. I can do that.
I want to know that one. That's gotta be you, Justin.
You guys.
Look at his forehead.
You just let me know and I'll give you who was.
Oh, that's funny.
So, Sal, you currently 44 years old and your biological age was 50.
Okay.
And so, you know, if you look at that, that's a plus six, which is a little bit different.
You scored better than 10% of others during this lab
and your rate of aging was 1.15,
just one 100th of a point less than Adam's.
Yes.
At this rate, you and I are gonna die at the same time.
10%ers.
Look at these guys.
We're buried together.
Yeah.
Good, very good epimetabolic.
Geriatrics over here.
Excellent.
All right, that's your consolation prize right there. So your shit sandwich right there. Map silver.
All right. Let's see by proxy we'll say who the winner is, but we'll go to the next person,
which is Doug. All right. So Doug, chronological age of 58 and biological age of 64. So that's plus six, but based on relative age score,
it's actually not as high.
So if we look at-
I was gonna say, because my score was like that.
So why did you make him win?
Because he's older.
Yeah.
Based off of his, so when you get to his age,
you'll be even a little bit higher.
CS I don't like this.
I'll be honest, I saw this result a few days ago,
and I didn't sleep well that night.
It can stress you out.
By the way, that'll make you age faster.
Yeah, I know.
I know.
It's increasing your score now.
It's like a vicious cycle here.
Getting less than a deep and REM sleep.
So you scored better, Doug, than 13% of people.
Wow.
At your age.
And your rate of aging was 1.10.
You're only losing one month a year.
13% or?
To be worse, you'd be losing two months.
Yeah.
All right.
Adam's always trying to win. The metabolic stuff. Every metabolic age was great on yours,
the index on yours was great.
Now here's what's weird about this Dr. Rol.
Of all the people that I know
who seem to be far younger than their age, it's Doug.
Yes.
Doug is like way more energy,
he's got more energy than all of us.
If we go out or whatever, he wants to stay out,
he wants to do whatever.
He's got tons of energy.
He looks young.
Oh, that cortisol.
Like what is that?
No, it really is just that.
The one thing that he knows, I mean, Doug is by far the healthiest in the world. He wants to stay out. He wants to do what? He's got tons of energy. He looks young. Like what is that? You know, what's going on?
No, it really is just that.
Like the one thing that he knows he would,
I mean, Doug is by far the healthiest
out of all of us.
Consistent with the nose.
The one thing though is his Achilles heel
is the stress and sleep, right?
Which are two of the biggest probably factors with this.
We looked at that on the minerals and metals test
and we saw that in the stress mood and metabolism.
Then we looked at your oar ring sleep stats
and those were a little bit less.
So that's the thing is I'm going to give you like eight or nine things that you can all work on and
every listener can work on. But for you, you don't need to work on all of them. You need to
like really dial in the 80-20 rule. 80% of the results will come with you,
most likely with stress and sleep. Yeah, absolutely.
Okay. Yeah, absolutely. For sure. And then keep in mind, you have to look at how many people,
58 years old are running this specific lab.
Oh, that's true.
I think the sample size is way smaller and I think the majority of them are
already focused on their health. So you're competing against like-
Oh, that's a self-selection bias, of course.
Yeah. And so where the most people are running like thirties and forties are running this
lab, I would say, for sure fifties as well
so not gonna say that but
Yeah, so anyway, I'm saying that I think you'll be able to dramatically improve this score for sure. Excellent
I gotta text my wife. She isn't an older man. So
Alright Justin, you finally won something
Yes
Finally win something Probably on winner, big winner.
All the sleeping hits.
All the sleeping hits.
What'd you say?
All the sleep, yeah.
All the sleeping hits.
It's key.
So you chronological age of 43, biological age of 44,
and so essentially neck and neck there,
and then 50% better.
I'm 44 actually, so yeah.
I'm actually authentically what I am.
Yeah, but the test was taken before you came. No.
Oh my goodness.
Okay.
All right.
So right on.
So you're going to see that in a second, your rate of aging.
So you scored 50% better than people of your age who took this lab.
And then yours is basically a one for one rate of aging, 1.02.
So like you said, if you put down 44 years old, you would have been a 1.0 for your rate of aging.
Cool, cool.
So right on that.
Good job, Justin.
All right.
The only authentic one here.
Yes.
When you seize what you get.
Right, and then epimetabolic.
Yours was still good, but more towards fat.
We want to make sure we're dialing in.
Hey, listen here, old man in and running your cardiovascular tasks and all
those things to just look at all that in advance.
All right.
I want to know if I'm more Neanderthal.
That one.
Yeah.
Yeah.
All right.
So there was only one Neanderthal in the group and I'm going to just verify that right now.
So I don't think skull size would tell you that. Hey, but you know what?
The, the Neanderthals were also supposed to be very intelligent and there's lots
of cool things. They were the hardiest. That's for sure.
We know that they could walk around with broken bones and all sorts of different
things. And they did. He does have the biggest ankles by far.
So nobody was a, um, E two, two, which is, um, the epoigenotype,
which is an allele, two, two,
but one of you was heterozygous,
which means you had one copy of it.
You guys want to take a guess who it was?
And this is the Neanderthal one?
This is the Neanderthal gene.
Who had a copy of it?
Who only had one copy, not both, but one.
Justin, I don't know.
I would say, you know, I don't know.
I don't know how you would even guess this.
No, it's impossible.
I mean, it's just, it's just kind of so funny.
I know my whole family's from,
I mean, I know exactly where they're from because both my
parents are from the same region.
They, and we did a genetic test of the middle East.
And so.
Yeah.
What does this exactly mean?
So what, what does it mean?
You have one of the, so.
That means your ancestor had sex with Neanderthals.
One of the oldest genes that you can have a specific
type of protein in the leal.
Okay.
Called your ApoE genotype.
It's essentially how you process fats and other things in the body.
And the people with this gene actually, they've been shown to not have as many
cardiovascular risks except for type three, which is a very rare hyper
cholesterol based syndrome, but not everybody has it.
And it's very protective.
It's very protective.
I can't have this.
There's no, I mean, I don't know, it might be me, but my
cholesterol is always, it doesn't matter what I eat. I can eat them. I can't have this. There's no, I mean, I don't know, it might be me, but my cholesterol is always, doesn't matter what I eat.
I could eat them.
I could eat so much saturated fat, whatever.
My cholesterol always measures real good.
So maybe that's not me.
We're into, Neanderthals were found mainly
in like the Northern regions.
Northern Europe.
Yeah.
That's why I guess me.
I think it's Justin.
It's Adam.
Adam, wow.
I said Adam early, dang.
Yeah. Wow.
Wow.
No way. He's got one copy. So. Can't win them all, but I got some.
Hey, if you can have one, it's a great one to have.
That's for sure.
Your ancestors didn't invent advanced tools.
It's been a long time.
They just started bringing back those Geico commercials
as well, you know?
They get right on.
It's so good. This looks like my uncle a little bit, you know, it's like getting right on.
It's so good. It does look like my uncle a little bit, you know what I'm saying?
So easy a caveman can figure it out.
Yeah, exactly.
When I was watching, I was watching football last week and they, they brought
those back and I was like, oh, it's so good.
Yeah.
Oh wow.
It's pretty funny.
Interesting.
So it's protective.
Huh?
Very protective.
Is it?
Yeah.
Okay.
Is there any other positive things about having that?
Uh, typically pretty balanced in terms of the, like I said, the lipid profile, um,
far less chance for Alzheimer's dementia.
Lots of same sex attraction I read about this.
Can't verify that, but, uh, I'll leave that up to you.
That's why they died off.
All right. Let's hear that.
Let's hear all the things in order of the hacks that we
should be doing. What are the big, what are the 80%? I want to reverse this. Yeah. So when we're
thinking about what causes us to age faster or age slower, I've really gone in depth on the research
on this. I mean, there's great gerontologists that really study this, that spend their lives on this. And my job is to run the labs, assimilate it, and then actually use it in practice.
And so there is diet, there's exercise, there's environmental toxins, such as the heavy metals
we spoke about. There's certain medications, drugs, and alcohol. There is overall mental health,
there's nutritional supplements that we know now will slow the rate of aging,
and then there's also the microbiome.
And then the biggest factor that we've talked about
before, sleep is a huge factor in this.
Yeah.
Wow.
That's, now what supplements, because I know
people are like, what's the problem?
Even though that's probably the least impactful,
what supplements slow this down?
Yeah.
So I'm happy to go through all of them.
Oh, good.
We can jump to the supplements though.
So there are, I teach something, so I teach
this in something called high performance health. And I tier supplements into four tiers.
So a lot of people like to jump to four, to the
fourth tier.
So the fourth tier is things like PQQ for the
mitochondria.
There are things like nicotinamide mononucleotide
or nicotinamide riboside that are great.
There's trans resveratrol.
Then there's extra special things like
spermidine, there's phycetin. There's trans-Respiratrol. Then there's extra special things like spermidine,
there's Fisetin. There's other factors that we
can use that we know help to remove what are
called senescent cells. So there's a few different
ways in which we age. There's like 11 different
factors, but it really comes down to what's called
the disposable soma theory on aging. I know we
talked about this, I think, just briefly on a time before that I was on, but what it essentially means is that you don't
really see aging until you start to get to your
like summer in your mid thirties to maybe
forties for some people.
And the reason is that during, uh, early years
in adolescence, you are ensuring that you can
create biological life, that you're healthy, hearty, sound, fertile.
And then once you're past really reproductive
based age, it's built into our body that then it
does not care as much about your hormones and
vitality, and then it starts to deteriorate on
a more rapid scale.
Right.
So we see that typically between that's why they
say like, oh, it's all downhill. Not really. Um, so it's not like, oh then it starts to deteriorate on a more rapid scale. Right.
So we see that typically between that's
where they say like, oh, it's all downhill.
Not really.
Um, somewhere between 40 and 65, it's this giant
gap of when the body starts to then, uh, break
down at a faster degree.
And it's only because, um, in the background,
when you're younger, your body is not taking care
of all the other processes that it needs to, cause your body can't do everything at once. So like, let's say you're younger, your body is not taking care of all the other processes that it needs to,
because your body can't do everything at once. So let's say you're getting high levels of heavy
metals and you're not sleeping and you're not eating well and you're playing sports,
your body's like, yeah, okay, but we're still going to keep producing lots of cortisol,
testosterone, dopamine, norepinephrine. And then your body after a while says,
oh, we can't produce as much of those anymore. And we have all this inflammation that's been happening in the background and it's not able to balance it.
So your mitochondria become weaker, so your mitochondria produce ATP and energy,
but what they also help to do is balance levels of inflammation in your body. And the more
antibiotics you take, the more viruses and chronic disease you get, the weaker the mitochondria
get, which then can't balance the inflammation. So now the inflammation is unchecked and it's also destroying your mitochondria.
So your body gets so much weaker with age.
Then we have something called senescent cells.
Senescent cells are basically called zombie cells.
They're cells that are no longer functioning, but they didn't get the sign
and the signal to create what's called apoptosis, which is basically
its own programmed cellular death.
And so that's, it's a good thing.
You don't want all the cells in your body
replicated all the time.
We get cancer.
Right, exactly.
So these things then are eliminated.
Well, you have cells in your body that are never eliminated.
The more senescent cells you have, the more inflammation.
Creates wrinkles in the skin, hair loss, grain of the skin,
not grain of the skin, but grain of the hair,
and the body begins to break down.
So some of these supplements help to remove
senescent cells and their topical creams as well.
While the other nutritional supplements help
with mitochondria, help with balancing inflammation,
help with what's called a citric acid cycle,
like NMN, one of the reasons why it's so popular
or vitamin B3 is because it literally gives you
back energy for the mitochondria.
So I've taken NMM, I've taken injectable NMM, I've done all, and I felt nothing.
I felt zero from it, but would I still show on a test that I'm taking it and-
Yes. That's the thing. None of those I can say are a dramatic boost unless your body has poor
mitochondria in the function of the first place. Like you might have, let's say a thousand
mitochondria per typical cell.
Your heart cells have like 5,000.
You can actually get tremendous benefit from
doing things to boost the mitochondria if you
were on the lower side in the first place.
Got it.
Besides that, they are great too.
That's why I call them tier four supplements.
You need to do all of your daily activated
multi, your omega threes, good probiotic, enzyme., good probiotic, enzyme, that's what's most
important so that you can also absorb all the nutrients of your food. Then you can move down
to a creatine, other factors there, magnesium, calcium, zinc. Then after that, okay, a little
bit more specialized, what might be more specialized? Collagen support. All of those are probably
still more important than taking the specialty ones.
Now, having said that, they're still important. Now, how do all those supplements rank to using
the infrared sauna and like a Juve light in comparison? Yeah, that's the great point because
it's not just about supplementation. So you want to go through these and you want to start with your
nutrition, your stress, and your nutrition,
stress, and sleep.
So if I say like, hey, what can we work on?
That's the most important, nutrition, stress, and sleep.
This fatty acid profile,
because I remember we did a test with you a while ago
where my omega-3 ratio was a little off
and I needed to increase my omega-3 intake.
You told me to take an omega-3 that was higher in DHA.
It was one of the products that you products. Higher in EPA than DHA.
EPA, sorry. Yes, yes.
Yep, absolutely.
Would that reduce my biological age?
Absolutely.
Oh, I see.
Yeah, absolutely. So what we're looking at, and this is actually, so this is the easiest way to
explain biological aging. You have more oxidative stress in your body than you essentially have
antioxidants, whether naturally made or from the environment
that can squelch all this free radical damage.
So it's like, it's unchecked oxidative stress from advanced glycation end products,
from over exercise or under exercise that enable
your body to maintain equilibrium.
You might not know the answer to this, but I'll
ask anyway, cause I don't know who else
I would ask.
I do know that I recently have quit using cannabis, but I'll ask you anyway, cause I don't know who else I would ask. I do know that, um, I recently have quit
using cannabis completely and I used it on a
relatively regular basis.
And I know it does affect, uh, the stages of
sleep, so it can help people go to sleep, but
it doesn't make your sleep as, as good.
Yes.
And I would say Adam and I were probably
the heaviest users of cannabis.
Could that be a contributor to faster
aging?
And cause I did read a study once that did
say that people whose cannabis have
accelerated biological age as well.
Could it be the sleep?
I believe that it is, and that's due to
Dr. Eamon's research.
Oh.
Cause doctor, like it's hard to find a whole
lot of people that have done more research in
the brain than Dr. Eamon.
And so he found this and I, so I did a whole
podcast on this.
And again, I love, I believe a rising tide lifts all boats.
I love giving credit where credit's due.
And so he does brain scans, but again, you can
go to him for Alzheimer's, you can do a full
body MRI.
But what he found, he compared to alcohol,
he compared alcohol, which we know damages
the brain.
For sure.
We know for sure.
For a fact.
He compared that against cannabis and cannabis
was worse for the brain than alcohol.
In terms of aging. In terms of aging.
In terms of aging.
Yeah.
Yeah.
The brain and the body.
So it's aging the brain, it's aging the body.
This may be why you and I, because you and I use most cannabis.
Yeah.
You know, and I know it affects sleep and negatively.
I mean, that's how I use it is before bed too.
So that's.
Actually.
So I'm still an advocate of cannabinoids and CBD.
Sure.
I'm still an advocate.
I'm an advocate of THC for certain individuals, Yeah. But it's one of those, I say, use it maybe for
12 to 16 weeks to get you off or through whatever
you're going through, like challenge wise in your
life right now, whether it's sleep or inflammation
or whatever, but then only as needed.
So I still use it, but I use it as needed.
So like, let's say I'm just, damn, I'm stressed
out because I've got all sorts of like life going on. Yeah. I'll use it, but I use it as needed. So like, let's say I'm just,
damn, I'm stressed out because I've got all sorts of like life going on. I'll use it.
Like I have no issues with that. I just use it ongoing.
I just came off of almost three months. It was like two, two and a half months of completely cold
Turkey and off. And then since then I've reintroduced it and that's what I'm trying to be more like,
I don't feel like I need it. It's not a stressful day.
I noticed that now,
because now it's been a while that I've been off
because you get that withdrawal.
We get these really weird, vivid dreams,
but now I'm back to normal, but I dream now.
I remember using cannabis.
I never would remember my dreams
because I think it affects that phase of sleep.
Phase of the REM, yes, absolutely.
So if you're not getting as much REM sleep,
which you're not typically getting with alcohol or cannabis,
then you're not getting those deeper
dream based states. That's the restorative part essentially of the mind, helps reduce anxiety
the next day, overwhelm, irritability, all of those things are tremendous. There's one more thing I
wanted to say along those lines with that is that again, anything that's good for us can be negative
if taken too far. That's basically just course. And actually taking an oral version of cannabis
is most likely better than smoking it.
Of course.
I want to state that too.
Yeah, of course.
Because the smoke is oxidative in and of itself.
Yeah.
And then I would help people transition off of
cannabis or alcohol with sleep by using a product
called Adrenal Soothe, which has phospholipidacin,
which reduces cortisol.
It's an amazing product.
Just great clinical research came out, this,
if you want to hear it, I'll go over it.
It contains ashwagandha, L-thionine and a few
others.
So we use that with full spectrum magnesium,
with a liquid melatonin.
And then, so we're off of then the cannabis and
then we actually reduce the dosage so that we
don't stop at cold turkey.
And then we reduce those other supplements as
well as able.
Wow. What was the data on phosphatidylserine you were saying? actually reduce the dosage so that we don't stop it, cold turkey. And then we reduce those other supplements as well as able.
Wow. What was the data on phosphatidylserine
you were saying?
So this is actually on Ashwagandha.
Oh, Ashwagandha, sorry.
It was a meta analysis of nine studies on
Ashwagandha.
And I said, listen, if you're stressed,
yes, I believe in journaling, I believe in
meditation, I believe in all those things.
But I remember back in the day when I was, every time I would meditate, I was so exhausted, I would just fall asleep. And when I would journal, I'm like, I believe in journaling, I believe in meditation, I believe in all those things. But I remember back in the day when I was,
every time I would meditate, I was so
exhausted, I would just fall asleep.
And when I would journal, I'm like, I don't
really believe any of this.
Like I was just, cause I was so stressed out
like back in my early twenties.
And so sometimes supplementation really does help.
Like it helps you get to a spot that you need to be.
So here's what they found over nine studies.
And I won't take you through each of the nine,
I actually did a podcast on all nine and it
showed anywhere from 250 milligrams
to 600 milligrams a day, reduced plasma levels
or salivary cortisol by 23 to 30%.
That's massive.
Which is unbelievable.
Massive.
Yeah, because you're not looking to take it to zero.
Like then you wouldn't have cortisol.
That's not a good thing.
You need it.
So it's an adaptogen that truly works
to help people just take the edge off stress.
It's tremendous.
Diet wise, besides healthy, which there's
kind of broad category, do we see less
oxidative stretch stress when someone is in a
ketogenic state versus one where they're using
glycogen just because of the process of producing
glycogen and all that is more oxidative or am I
just shooting in the dark here?
It's, I think it's a good theory, but that has not held up yet.
What's held up the most right now is still
a Mediterranean diet.
That's why if you read Dr. Neer's work or
David St. Clair's work or any of like the
gerontologists in this space, they're saying,
they're not saying that you can't eat meat,
you can, absolutely.
They're saying eat, Volta or Alango, eat fish
a few times a week.
What you want to do though is balance it with polyphenols.
That's the biggest thing is that people are not getting
enough fruits and vegetables, just brightly colored things.
Olive oil is a really good source, right?
And olive oil is fantastic.
High quality.
Yeah.
Yes, exactly.
I'm recently, I'm going ketogenic, but this is
all just for mental reasons and I'll do it every once in a while.
So I don't stay there, but I use a lot of olive oil when I'm going ketogenic, just this is just for mental reasons and I'll do it every once in a while. So I don't stay there, but I use a lot of olive oil
when I'm going ketogenic just about my fat.
So that's good news.
I have no issues with people doing a cyclic
ketogenic diet using mainly olive oil and avocado
as their predominant fats for about three to four weeks.
Yeah.
That's typically like the maximum that I would say
because it's not all rainbows, unicorns, and sunshine.
Like there's downsides to it as well.
Yeah.
I just noticed cognitive, I guess, sharp with it,
but after about a month or two, then I tend to come out of it.
So.
Yeah.
Without a doubt.
And I think the goal is metabolic flexibility.
That's right.
You can go with fats, you can go with out-carbs.
You can like, you're able to handle it unless you have a specific event.
And then you're training for that event and you could be more
fat adapted or more towards a glucose.
Yeah, we recently had a trainer course launch
and that's why I did it, it was for the mental
sharpness and so.
Nice.
Yeah, absolutely.
And even people who are not a keto based diet,
I will say we don't use them in our practice.
If you add specific exogenous ketones, it does
actually help seem to work as well.
So yeah, without a doubt.
I mean, even if we don't use it in our practice,
cause you don't need to use old things, like
there's different ways to get well, right?
There's different ways to get results.
Um, and so everybody has like a methodology,
but that is for sure one that works.
Another one I wanted to add is just specifically
on the brain.
I think that this is really important.
Um, it's called BDNF, brain derived neurotropic
factor.
So we're starting to hear more and more about this because typically the more BDNF, brain derived neurotropic factor. So we're starting to hear more and more about this
because typically the more BDNF, it's almost like an
inverse relationship. More BDNF, less oxidative
stress in the brain, less likelihood of Alzheimer's
and dementia. Because if, and I know we talked about
this before, but I would talk about this every show
if I could. It's people are living to 74 to 77 years
old with the heart disease, the high blood pressure,
diabetes, cancer, and Alzheimer's. So those are the five reasons why people die essentially.
It's not like they're healthy and they die. It's like they get sick, sick, sick, sick, sick.
For like 20 years to 30 years, right? But if you don't get any one of those five,
the next causes of mortality are literally COPD, which is almost unheard of in people
that don't smoke or chemical irritants or emphysema,
which is basically a version.
And then it's literally accidental death,
kidney based issues.
And the kidney based issues typically come from
high blood pressure and the medications you're
put on or type two diabetes.
And then the literally the injuries are motorcycle
accidents and falling off your roof, like legitimately.
Yeah, because if you're 75 and you feel healthy as hell,
you're gonna buy a motorcycle or fix your wheels.
Right.
Cause that's what's gonna happen.
Well, the thing is though,
you get at least an extra 10 to 15 years of life expectancy
if you don't get those five.
I was just gonna say, I've read data on this and they say,
if you've made it to the,
whatever the current life expectancy is,
and you don't have these major issues,
you can expect to live a lot longer.
A hundred percent.
Yeah.
But also better quality of life, right?
So there's health span and there's lifespan.
And I, sorry, I skipped over that.
Lifespan is how long you live, but for the
most part, people are diseased.
They have a chronic based disease in their 40s
and then they are on medication then for the rest
of their life.
That's our typical population.
Right.
It's usually statin drug or it's on even things like Prilosec for acid reflux.
Yeah.
Well, we know that can lead to barrens
and solvigil cancer.
Yeah.
Or it's high blood pressure or it's type two
diabetes and the likelihood that you have
multiple of those is very high because once
you get one, you medicate for it and then you
pretend like it's not an issue and then the
inflammation manifests somewhere else.
Yeah.
And then cancer is the only wild card and the
only thing I can say is you try to do everything right, but you run your full body scans
and you find it early before it's stage three or
stage four, when you have a higher likelihood of
being able to treat it either naturally or
conventional medicine or a combination of both.
And I can share some great studies on that as well.
Yeah.
Strength training will reduce your all cause of
cancer by like something like 20 something percent
just by building more muscle.
That was a recent thing.
I'd love to hear the research on that. How many times a week was it? Do you know and what type of exercises? Oh, you're right. will reduce your all cause of cancer by something like 20 something percent, just by building more muscle.
I'd love to hear the research on that. How many times a week was it? Do you know? And what type of exercises?
Oh, two to three days a week of strength training. We're talking about bodybuilders or anything like that.
It was just having the muscle because muscle seems to be protective against cancer.
Yes, a hundred percent. And it's also, I would love to see too, it's like if you're doing that,
are you also doing these things right as well? But in and of itself, muscle is important because what does it do? It helps strengthen
the mitochondria, helps balance the immune system to a greater degree. So there's a lot
of benefits to that. So one of those things is just like you said, two to three days a week
can improve biological age for strength training, not overdoing it, overtaxing the nervous system
or too much breakdown. But believe it or not, and this is one that I
don't love, but I'm recommitting for this year
to do it is cardiovascular zone two, cardio.
And it's not a little bit.
It's actually like an hour and a half a week of
zone two cardio is kind of your baseline for that.
So it's a brisk walk, not a regular walk, but a brisk walk or uphill incline walking
is essentially that zone two cardio that is maybe boring or so, but is dramatically beneficial for
your biological age and rate of aging. Yeah. Like even more so for telomeres, because telomeres is
not the end all be all, but it was one of the like five things that
was a big one to improve overall telomere length
and methylation sites was aerobic based capacity.
And you said 90 minutes?
A week.
Yeah.
Uh, that would be the minimum.
It's more like 150, like 30 minutes or so, five
days a week.
Oh, okay.
Yeah.
So it's a good amount.
Okay.
You could do it not every day.
You could do it every other day, but they've also found this. If you walk 8,500, 7,500 seems to be the minimum to 10,000 steps a
day. You reduce all cause mortality by over 23%. So that's a pretty fantastic number for people just
to walk. Yeah. I mean, that's a good point to bring because I've heard people ask questions like,
what's this arbitrary 10,000 step number? Does it even matter?
Does it make a difference in that right there, just right there?
It is somewhat arbitrary because again, it depends on the individual.
Depends on what else, if you're strength training two to three days a week as well,
do you really need a 10? Oh, you might be okay with 7,500. I think it depends on what are your
genetics for your cardiovascular issues as well. So there's a lot that goes on, how many calories
you need to burn, even though it's a slow burn.
But they also found it wasn't even every day.
It was five days a week or more.
So 10,000, so 7,500 to 10,000 steps, five days a week or more. So you don't have to feel bad about missing a day.
I have a question for you.
Cause if you look at longevity online, what you typically will find is hormone
therapy, growth hormone, testosterone, and women they'll do estrogen progesterone.
Have you seen those things being added
affecting age or is that more of a just, you
feel different type of thing?
Feel different and yes, in terms of health span,
but we have not seen any correlation that
I've seen in terms of lifespan.
And I'm actually waiting for that because we
just don't know yet.
We don't know if it's going to extend life or
there is a theory that the more hormone you're
taking right now, the more you're covering up,
going back to the disposable soma theory.
Sure.
Are you covering up the deficiencies or
toxicities you may have that would ordinarily
make you feel like, listen, I got to do something.
That's right.
So that's- Have you seen a change in biological age? Like would you have people who are like, listen, I gotta do something. That's right. So that's-
Have you seen a change in biological age?
Like would you have people who are like,
oh, I went on testosterone replacement there,
I went on growth hormone, whatever,
and then you see a change there or does it not affect-
We need more people to see that.
I don't have that data right now.
Yeah, I'd like to see it.
It'd be hard too to tease out the behaviors
because of that too though, right?
Of course, yeah, more testosterone, more energy.
Right, right, I mean, because I remember what I felt like
with really low testosterone,
I just did not want to move,
I didn't want to exercise,
and then all of a sudden balancing that out.
Now I'm eager to lift and more active,
and so that's kind of tough to try to tease out.
It's fascinating because mental health
is one of the issues with either increased aging or less.
They found that people who lived to be 100 years old,
they were just less stressed about life, like legitimately.
They didn't have the perfect diet, although
yes, they had, you know, the right amount of
fiber and they typically, they did things that
were good, right?
They did some intermittent fasting.
We even talked about that, you know, 12 hours
to 16 hours a day.
They didn't overeat.
That was a big thing.
They mainly walked.
They didn't necessarily do weight training.
I don't think it's important because if you
break your hip at 70 years old, the likelihood
you go downhill real fast is highly likely.
And so those things are important.
Uh, but mental health is a huge factor in how
you overall view life and you view your happiness.
Yeah.
That's a big one.
Hormones is part of that.
Uh, my goal is to help people as naturally
for as long as I can.
And then when needed, as we spoke about before,
you can augment and you take it multiple times per week, which is
what now finally it's happening in the industry
rather than like once a month or twice a month.
And then you get this high level and then you
see it drop down.
So you're kind of like, um, getting this smaller
amount throughout the day, how your body would
normally produce it rather than a large amount.
And then come back down, which could lead to red
blood cells issues, coagulation, if the, if the
amount is super physiological.
So it's always about finding that right level for you to be able to do that. would normally produce it rather than a large amount and then come back down, which could lead to red blood cells issues, coagulation if the,
if the amount is super physiological.
So it's always about finding that right
level for you.
And, um, yeah, it's about, I mean, it really
is about balance and bio individuality.
How often do you recommend someone take this test?
You said every six months?
I would say you can safely do this every four
to six months.
And then in the future, we'll talk about three years from now.
I think you'll be able to do it about every 12 weeks.
Like you'll be able to really get results faster.
So I'm doing mine every three to four months because what I recommend for everybody out there is that you don't change everything at once.
Change two variables. And so you can actually see if it's working.
Because you have your whole life to be able to like look at this lab.
And so what I recommend is, you know, pick two
that you know that you can actually accomplish.
Not maybe that you need that to do, but pick
two that you can accomplish.
Yeah, sure.
Supplements could be one, but maybe it's
intermittent fasting.
Maybe it's diet.
Maybe it is working just on your sleep, just
on reducing stress.
And then, okay, see how does that move the needle?
But you have to keep in mind that, because I've actually seen it. So the first time I ran, well, see how does that move the needle? But you have to keep in mind that,
because I've actually seen it. So the first time I ran, well, as I was improving,
I was like 0.86 and then I was like a little bit lower
and then I was a 0.69, which was phenomenal.
I was like, okay, this is great.
But then I ran it again and actually was more stressed.
And I wasn't doing the same steps in cardiovascular
that I wanted to be doing.
And I went up to a 0.71.
And you can say, oh, well, maybe that's just the inaccuracy. It could be, right? But all I wasn't
is dialed in. Dialed it back in, four months later, took it 0.67. And I went from a biological age of
like 36 to then my lowest, which was 32. And so these things really do matter. And what I say is
dial in the biggest ones, which is sleep, stress,
and nutrition if you can first, just pick one and
then continue to work on it.
And then just keep in mind, if you just had a
newborn baby, you just did all these things,
but you probably don't test.
Unless you want to see.
Well, you want to see what happens.
You can actually see the negative.
You can see that this is a negative result.
And where do people get this one?
So we set up a link.
It's called stevencobral.com slash bio age. That'll be a discount for your community.
Okay.
And there are, like I said, there's four different
companies that do this. The reason why I recommend
this first biological age that we went through is
because it is maybe not as liberal with your overall
biological age, but it's going to be, it's used as
Dr. Steven Horvath's clock. So he's a very well renowned gerontologist,
probably great to have.
He actually would have to zoom in cause I don't
even know that he lives in the US.
Um, but it looks at your APOE genotype and your
MTHFR and that's information that you absolutely
should have to base your nutrition off of it and
your overall lifestyle and the other biological
age tests don't have it.
And it's Steven Cabral, S-T-E-P-H-E-N and then
cabral.com forward slash bio age.
This test was pretty easy to take by the way.
So people listen, it's a blood test, but it's
easy, we did it ourselves here at the studio, right?
You did a simple finger prick.
Very easy.
Very easy.
Simple finger prick, very little blood.
And again, they're just using those specific
cells, looking at the methylation points on those
cells, taking your average andlation points on those cells,
taking your average and then showing you what you can improve.
So yeah, hopefully that was helpful.
Now I know that when we were all somewhere and there's not enough seats for
everybody to sit down, I'll give Adam a seat cause you always give the older.
We should do a follow up, you know, it's on now. So yeah,
like I said, my, uh, my colleagues and I, we dork out on this and we try to beat each
other in terms of biological age.
Cause if you're doing that is actually, so it's fun to try to beat the system and beat
your own body, but also just, you know, have fun and compare with others.
I think it's a healthy competition for all of us.
I appreciate it.
Thanks for coming on.
My pleasure.
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